Trial reportItalian journal of pediatrics2010
Perfusion index variations in clinically and hemodynamically stable preterm newborns in the first week of life.
Trial report in Italian journal of pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Early multi-system physiological biomarkers of bronchopulmonary dysplasia in preterm infants: a matched case-control study based on bedside monitoring.Frontiers in medicine · 2026Article
- Performing Pulse Oximetry Screening in the Delivery Room Identified Newborn Infants Who Required Early Medical Attention.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Swaddle bath vs. tub bath for physiological outcomes and skin microbiota in late preterm infants: a randomized controlled trial.Frontiers in pediatrics · 2025Article
- Plethysmograph Variability Index - A Simple Tool to Understand the Rhythm of Life Among Term Neonates.Indian journal of pediatrics · 2024Article
- Distribution and reference values of peripheral perfusion index in neonates from population-wide screening.BMJ paediatrics open · 2024Article
- Role of Perfusion Index and Pulse Variability Index in the Assessment of Neonatal Hemodynamics: A Systematic Review.Cureus · 2023Review
- Evaluation of tissue perfusion status in moderate to late preterm.Physiological research · 2022Article
- The perfusion index histograms predict patent ductus arteriosus requiring treatment in preterm infants.European journal of pediatrics · 2021Article
- Optimizing Nutritional Strategies to Prevent Necrotizing Enterocolitis and Growth Failure after Bowel Resection.Nutrients · 2021Review
- Observational
- Perfusion index and left ventricular output correlation in healthy term infants.European journal of pediatrics · 2017Observational
- Perfusion Index in Very Low Birth Weight Premature Infants During Their First 2 Weeks of Life.Biological research for nursing · 2017Article
- Reference values of perfusion indices in hemodynamically stable newborns during the early neonatal period.European journal of pediatrics · 2014Article
- A pilot study to examine maturation of body temperature control in preterm infants.Journal of obstetric, gynecologic, and neonatal nursing : JOGNNArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe perfusion index, derived from the pulse oximeter signal, seems to be an accurate predictor for high illness severity in newborns. The aim of this study was to determine the perfusion index values of clinically and hemodynamically stable preterm newborns in the first week of life.
methodsPerfusion index recordings were performed on the first, third and seventh day of life on 30 preterm newborns. Their state of health was assessed according to clinical and behaviour evaluation and to the Score for Neonatal Acute Physiology.
resultsThe median(interquartile range) perfusion index values were 0.9(0.6) on the first, 1.2(1.0) on the third, and 1.3(0.9) on the seventh day, with a significant increase between the first and the third day.
conclusionsPerfusion index proved to be an easily applicable, non-invasive method for monitoring early postnatal changes in peripheral perfusion. Its trend during the first week of life suggests that its clinical application should take age into account. Further studies are needed to obtain reference perfusion index values from a larger sample of preterm newborns, to identify specific gestational age-related cut-off values for illness and to test the role of perfusion index in monitoring critically ill neonates.
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