ReviewReproductive biology and endocrinology : RB&E2010
Management of the infertile couple: an evidence-based protocol.
Review in Reproductive biology and endocrinology : RB&E, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
74 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Glutathione-S-transferases M1/T1 gene polymorphisms and male infertility risk in Chinese populations: A meta-analysis.Medicine · 2019Pooled it
- Transcutaneous electrical acupoint stimulation improves endometrial receptivity resulting in improved IVF-ET pregnancy outcomes in older women: a multicenter, randomized, controlled clinical trial.Reproductive biology and endocrinology : RB&E · 2022Trial
- Study of the effects of oral zinc supplementation on peroxynitrite levels, arginase activity and NO synthase activity in seminal plasma of Iraqi asthenospermic patients.Reproductive biology and endocrinology : RB&E · 2014Trial
- The Relationship Between Infertility Stress and Awareness/Utilization of Benefits Under the 'Family and Youth Support Law' Among Iranian Infertile Couples: A Cross-Sectional Study.Health science reports · 2026Article
- Photothermal Resilience of Biopolymer-Based Btk Microcapsules: Implications for Sustainable Pest Control.ACS omega · 2026Article
- Survey on the Public Opinion and Attitudes Toward Uterus Transplantation in Hungary.Clinical transplantation · 2025Article
- The Potential Role of Chromosomal Polymorphic Variations Attributed to Male Infertility: A Retrospective Cohort Study.Journal of reproduction & infertility · 2025Article
- Knowledge, Attitudes, and Practices of the General Population Regarding Peripheral Blood Chromosomal Testing in the Premarital or Preconception Context.Molecular genetics & genomic medicine · 2025Article
- Epidemiological disease burden and annual, nationwide health insurance treatment cost of female infertility based on real-world health insurance claims data in Hungary.BMC health services research · 2025Article
- Novel variants in DNAH9 are present in two infertile patients with severe asthenospermia.Journal of human genetics · 2025Article
- Psychological health conditions of ART treated infertile couples: a 4-years prospective study.Frontiers in psychology · 2025Article
- Exploratory study on the application of laser-induced cavitation bubble in the treatment of fallopian tube obstruction.PloS one · 2025Article
- Diacerein mitigates endocrine and cardio-metabolic disruptions in experimental PCOS mice model by modulating AdipoR1/ PON 1.BMC endocrine disorders · 2024Article
- Endometriosis in infertile women: an observational and comparative study of quality of life, anxiety, and depression.BMC women's health · 2024Observational
- The relationship between duration of infertility and clinical outcomes of intrauterine insemination for younger women: a retrospective clinical study.BMC pregnancy and childbirth · 2024Article
- 'It's about time': policymakers' and health practitioners' perspectives on implementing fertility care in the Gambian health system.BMC health services research · 2024Article
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- Phenotypic variability in two female siblings with oocyte maturation arrest due to a TUBB8 variant.BMC medical genomics · 2023Article
- Exosomal miR-205-5p Improves Endometrial Receptivity by Upregulating E-Cadherin Expression through ZEB1 Inhibition.International journal of molecular sciences · 2023Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfertility is defined as inability of a couple to conceive naturally after one year of regular unprotected sexual intercourse. It remains a major clinical and social problem, affecting perhaps one couple in six. Evaluation usually starts after 12 months; however it may be indicated earlier. The most common causes of infertility are: male factor such as sperm abnormalities, female factor such as ovulation dysfunction and tubal pathology, combined male and female factors and unexplained infertility.
objectivesThe aim of this study is to provide the healthcare professionals an evidence-based management protocol for infertile couples away from medical information overload.
methodsA comprehensive review where the literature was searched for "Management of infertility and/or infertile couples" at library website of University of Bristol (MetaLib) by using a cross-search of different medical databases besides the relevant printed medical journals and periodicals. Guidelines and recommendations were retrieved from the best evidence reviews such as that from the American College of Obstetricians and Gynaecologists (ACOG), American Society for Reproductive Medicine (ASRM), Canadian Fertility and Andrology Society (CFAS), and Royal College of Obstetricians and Gynaecologists (RCOG).
resultsA simple guide for the clinicians to manage the infertile couples.
conclusionsThe study deploys a new strategy to translate the research findings and evidence-base recommendations into a simplified focused guide to be applied on routine daily practice. It is an approach to disseminate the recommended medical care for infertile couple to the practicing clinicians.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.