Evidence map›Paper›PMID 20205485›Full record

ReviewDrugs2010

Atypical antipsychotics for acute manic and mixed episodes in children and adolescents with bipolar disorder: efficacy and tolerability.

Manpreet K Singh, Terence A Ketter, Kiki D Chang

Abstract readReview
In one paragraph

Review in Drugs, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Manpreet K SinghDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA. mksingh@stanford.edu
Terence A Ketter
Kiki D Chang

Funding

Genetic and Neurobiologic Risk Factors for Bipolar Disorder DevelopmentR01MH077047 · NIMH · STANFORD UNIVERSITY · PI CHANG, KIKI D · 2007 to 2011
$2.9M
Emotion Regulation in Children of Parents with Bipolar DisorderK23MH085919 · NIMH · STANFORD UNIVERSITY · PI SINGH, MANPREET K · 2009 to 2013
$866k
NIMH NIH HHS K23 MH085919NIMH NIH HHS R01 MH077047
6 · The paper itself

Abstract

The diagnosis of bipolar disorder (BD) in children is increasing, and often requires a comprehensive treatment plan to address a complex array of symptoms and associated morbidities. Pharmacotherapy, in combination with psychotherapeutic interventions, is essential for the treatment and stabilization of disrupted mood. Current evidence collectively demonstrates, by randomized controlled design, that atypical antipsychotics have efficacy for the treatment of acute manic or mixed symptoms in children and adolescents with BD. Additional longitudinal and biological studies are warranted to characterize the effects of atypical antipsychotics on all phases and stages of bipolar illness development in children and adolescents.

Indexed as

Acute DiseaseAdolescentAntipsychotic AgentsBipolar DisorderChildHumansAntipsychotic Agents

Identifiers

PMID20205485
PMCPMC2882025

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.