Evidence map›Paper›PMID 20204610›Full record

ArticleJournal of molecular evolution2010

The rate of unequal crossing over in the dumpy gene from Drosophila melanogaster.

Amber Carmon, Matthew Larson, Marta Wayne, Ross MacIntyre

Abstract read
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In one paragraph

Article in Journal of molecular evolution, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. High mechanical property silk produced by transgenic silkworms expressing theFrontiers in bioengineering and biotechnology · 2024
    Article
  2. Article
  3. Evolution of Protein Domain Repeats in Metazoa.Molecular biology and evolution · 2016
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amber CarmonDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Matthew Larson
Marta Wayne
Ross MacIntyre

Funding

Alternative splicing in the complex Drosophila dumpy geneR21HD059073 · NICHD · CORNELL UNIVERSITY · PI MACINTYRE, ROSS JOSEPH · 2009 to 2010
$424k
6 · The paper itself

Abstract

The PIGSFEAST (PF) exon of the Drosophila dumpy gene is undergoing concerted evolution by the process of unequal crossing over. We have developed a long-range PCR-based assay to amplify the approximately 12 kb long exon which contains variable numbers of 303 or 306 nt long repeats in a tandem array. We applied this procedure to mutation accumulation lines of Drosophila melanogaster established by M. Wayne and L. Higgins. Nine new repeat length variants were found in these lines allowing us to measure the rate of unequal crossing over in the PF exon. The rate, which for several reasons is an underestimate, is 7.05 x 10(-4) exchanges per generation.

Indexed as

AnimalsCrossing Over, GeneticDrosophila melanogasterDrosophila ProteinsExtracellular Matrix ProteinsGene FrequencyModels, BiologicalMutationPolymerase Chain ReactionPolymorphism, GeneticRepetitive Sequences, Nucleic AcidDPY protein, DrosophilaDrosophila ProteinsExtracellular Matrix Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.