ArticleEuropean journal of nuclear medicine and molecular imaging2010
(18)F-FDG PET/CT bone/bone marrow findings in Hodgkin's lymphoma may circumvent the use of bone marrow trephine biopsy at diagnosis staging.
Article in European journal of nuclear medicine and molecular imaging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2014Guideline
- Early treatment response evaluation in patients with diffuse large B-cell lymphoma--a pilot study comparing volumetric MRI and PET/CT.Molecular imaging and biology · 2011Trial
- How I treat advanced Hodgkin lymphoma - a global view.British journal of haematology · 2020Review
- Review
- (2S,4R)-4-[Molecular imaging and biology · 2019Article
- Response to the letter by Adams and Kwee, entitled: "Unproven value of end-of-treatment FDG-PET in Hodgkin lymphoma".European journal of nuclear medicine and molecular imaging · 2017Article
- Utility of 18F sodium fluoride PET/CT imaging in the evaluation of postoperative pain following surgical spine fusion.Musculoskeletal surgery · 2017Article
- Advanced Hodgkin's lymphoma: End-of-treatment FDG-PET should be maintained.European journal of nuclear medicine and molecular imaging · 2017Article
- Article
- Efficacy ofMolecular imaging and radionuclide therapy · 2017Article
- The role of FDG-PET in Hodgkin lymphoma.Contemporary oncology (Poznan, Poland) · 2017Review
- Mechanisms underlying the association between obesity and Hodgkin lymphoma.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016Review
- FDG-PET imaging in hematological malignancies.Blood reviews · 2016Review
- New Perspectives Offered by Nuclear Medicine for the Imaging and Therapy of Multiple Myeloma.Theranostics · 2016Article
- Can Positron Emission Tomography and Computed Tomography Be a Substitute for Bone Marrow Biopsy in Detection of Bone Marrow Involvement in Patients with Hodgkin's or Non-Hodgkin's Lymphoma?Turkish journal of haematology : official journal of Turkish Society of Haematology · 2015Article
- Imaging in Lymphoma: The Key Role of Fluorodeoxyglucose-Positron Emission Tomography.The oncologist · 2015Review
- Article
- 2-deoxy-2-((18)F)fluoro-D-glucose positron emission tomography/computed tomography imaging in paediatric oncology.World journal of radiology · 2014Review
- Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2014Article
- Characterizing bone marrow involvement in Hodgkin's lymphoma by FDG-PET/CT.European journal of nuclear medicine and molecular imaging · 2014Article
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12 authors.
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Abstract
purposeAccurate staging of Hodgkin's lymphoma (HL) is necessary in selecting appropriate treatment. Bone marrow trephine biopsy (BMB) is the standard procedure for depicting bone marrow involvement. BMB is invasive and explores a limited part of the bone marrow. (18)F-FDG PET/CT is now widely used for assessing response to therapy in HL and a baseline study is obtained to improve accuracy. The aim of this retrospective analysis was to assess whether routine BMB remains necessary with concomitant (18)F-FDG PET/CT.
methodsData from 83 patients (newly diagnosed HL) were reviewed. All patients had received contrast-enhanced CT, BMB and (18)F-FDG PET/CT. Results of BMB were not available at the time of (18)F-FDG PET/CT imaging.
resultsSeven patients had lymphomatous involvement on BMB. Four patients had bone involvement on conventional CT (two with negative BMB). All patients with bone marrow and/or bone lesions at conventional staging were also diagnosed on (18)F-FDG PET/CT scan. PET/CT depicted FDG-avid bone/bone marrow foci in nine additional patients. Four of them had only one or two foci, while the other had multiple foci. However, the iliac crest, site of the BMB, was not involved on (18)F-FDG PET/CT. Osteolytic/sclerotic lesions matching FDG-avid foci were visible on the CT part of PET/CT in three patients. MRI ordered in three other patients suggested bone marrow involvement. Interim and/or end-therapy (18)F-FDG PET/CT documented response of FDG-avid bone/bone marrow foci to chemotherapy in every patient.
conclusion(18)F-FDG PET/CT highly improves sensitivity for diagnosis of bone/bone marrow lesions in HL compared to conventional staging.
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