ReviewJournal of biomedicine & biotechnology2010
Regulation of gene expression in protozoa parasites.
Review in Journal of biomedicine & biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Analysis ofMicroorganisms · 2026Article
- Screening and Structural Characterization of Heat Shock Response Elements (HSEs) inInternational journal of molecular sciences · 2024Article
- Dual RNA-seq to catalogue host and parasite gene expression changes associated with virulence of T. annulata-transformed bovine leukocytes: towards identification of attenuation biomarkers.Scientific reports · 2023Article
- Differentially expressed transcripts of Tetracapsuloides bryosalmonae (Cnidaria) between carrier and dead-end hosts involved in key biological processes: novel insights from a coupled approach of FACS and RNA sequencing.Veterinary research · 2023Article
- A Comparison of Stage Conversion in the Coccidian ApicomplexansFrontiers in cellular and infection microbiology · 2020Review
- An in vitro characterisation of the Trichomonas vaginalis TATA box-binding proteins (TBPs).Parasitology research · 2019Article
- An NADeLife · 2018Article
- mRNA export in the apicomplexan parasite Toxoplasma gondii: emerging divergent components of a crucial pathway.Parasites & vectors · 2018Review
- Challenges and Persistent Questions in the Treatment of Trichomoniasis.Current topics in medicinal chemistry · 2017Review
- Identification of repressive and active epigenetic marks and nuclear bodies in Entamoeba histolytica.Parasites & vectors · 2016Article
- Entamoeba histolytica: protein arginine transferase 1a methylates arginine residues and potentially modify the H4 histone.Parasites & vectors · 2015Article
- Article
- Male infertility: a public health issue caused by sexually transmitted pathogens.Nature reviews. Urology · 2014Review
- The Tc1/mariner transposable element family shapes genetic variation and gene expression in the protist Trichomonas vaginalis.Mobile DNA · 2014Article
- The small GTPase EhRabB of Entamoeba histolytica is differentially expressed during phagocytosis.Parasitology research · 2013Article
- Trichomoniasis: evaluation to execution.European journal of obstetrics, gynecology, and reproductive biology · 2011Review
- Comparative genomics of proteins involved in RNA nucleocytoplasmic export.BMC evolutionary biology · 2011Article
- In Silico Prediction of Evolutionarily Conserved GC-Rich Elements Associated with Antigenic Proteins of Plasmodium falciparum.Evolutionary bioinformatics online · 2011Article
- Emerging functions of transcription factors in malaria parasite.Journal of biomedicine & biotechnology · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infections with protozoa parasites are associated with high burdens of morbidity and mortality across the developing world. Despite extensive efforts to control the transmission of these parasites, the spread of populations resistant to drugs and the lack of effective vaccines against them contribute to their persistence as major public health problems. Parasites should perform a strict control on the expression of genes involved in their pathogenicity, differentiation, immune evasion, or drug resistance, and the comprehension of the mechanisms implicated in that control could help to develop novel therapeutic strategies. However, until now these mechanisms are poorly understood in protozoa. Recent investigations into gene expression in protozoa parasites suggest that they possess many of the canonical machineries employed by higher eukaryotes for the control of gene expression at transcriptional, posttranscriptional, and epigenetic levels, but they also contain exclusive mechanisms. Here, we review the current understanding about the regulation of gene expression in Plasmodium sp., Trypanosomatids, Entamoeba histolytica and Trichomonas vaginalis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.