ReviewGerman medical science : GMS e-journal2010
Human intestinal spirochetosis--a review.
Review in German medical science : GMS e-journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 110 citations in OpenAlex.
- Exploratory characterization of gut microbiota and cognitive profiles in adolescents with subthreshold depression: a shotgun metagenomics sequencing study.Npj mental health research · 2026Article
- Human intestinal spirochetosis presenting as colonic ulceration in an immunocompetent 65-year-old man.Infection · 2026Article
- The Basophilic Fringe: A Case Report of Intestinal Spirochetosis in a Patient With Chronic Diarrhea.Cureus · 2026Article
- Human Intestinal Spirochetosis as a Cause of Chronic Diarrhea in an Immunocompetent Patient: A Case Report.Cureus · 2026Article
- Article
- Intestinal giardiasis and spirochetosis causing unintentional weight loss in a 40-year-old man.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025Article
- Coexistence of Intestinal Spirochetosis and Colorectal Cancer: Could the Coil be Carcinogenic?ACG case reports journal · 2024Article
- Colonizing the Unlikely:ACG case reports journal · 2024Article
- A Case Study: Incidental Finding of Human Intestinal Spirochetosis in Screening Colonoscopy.Cureus · 2024Article
- Intestinal Spirochetosis: To Treat or Not to Treat.Cureus · 2024Article
- Spirochetosis Mimicking Acute Appendicitis: Clinical Report and Review of the Literature.Inflammatory intestinal diseases · 2023Article
- A Rare Cause of Diarrhea: Intestinal Spirochetosis in an HIV-Positive Patient.ACG case reports journal · 2023Article
- Article
- Increased Prevalence of Symptomatic Human Intestinal Spirochetosis in MSM with High-Risk Sexual Behavior in a Cohort of 165 Individuals.Tropical medicine and infectious disease · 2023Article
- A Cross-Sectional Study of Potential Antimicrobial Resistance and Ecology in Gastrointestinal and Oral Microbial Communities of Young Normoweight Pakistani Individuals.Microorganisms · 2023Article
- Identification of intestinal and fecal microbial biomarkers using a porcine social stress model.Frontiers in microbiology · 2023Article
- Every colon shouldn't have a silver lining: an atypical case of colitis caused by a 'commensal' organism.Frontline gastroenterology · 2023Article
- Article
- The Analysis of Transcriptomes and Microorganisms Reveals Differences between the Intestinal Segments of Guinea Pigs.Animals : an open access journal from MDPI · 2022Article
- Pathobiology and dysbiosis of the respiratory and intestinal microbiota in 14 months old Golden Syrian hamsters infected with SARS-CoV-2.PLoS pathogens · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human intestinal spirochetosis (IS) is a condition defined histologically by the presence of spirochetal microorganisms attached to the apical cell membrane of the colorectal epithelium. Intestinal spirochetes comprise a heterogeneous group of bacteria. In humans, Brachyspira aalborgi and Brachyspira pilosicoli predominate. Prevalence rates of IS are low where living standards are high, in contrast to poorly developed areas where IS is common. Homosexuals and HIV-infected individuals are at high risk of being colonized. Clinical significance in individual cases has remained unclear up to now. A review of the literature assumes that invasion of spirochetes beyond the surface epithelium may be associated with gastrointestinal symptoms which respond to antibiotic treatment (metronidazole), whereas individuals lacking this feature may be mostly asymptomatic. Of unknown reason, homosexual and HIV-positive men as well as children are more likely to be symptomatic irrespective of invasion. Rare cases of spirochetemia and multiple organ failure have been reported in critically ill patients with IS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.