Evidence map›Paper›PMID 20200419›Full record

Trial reportJournal of dental research2010

Implication of ethanol wet-bonding in hybrid layer remineralization.

J Kim, L Gu, L Breschi, L Tjäderhane, K K Choi, D H Pashley, F R Tay

Open access · greenAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of dental research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Biomimetic remineralization of dentin.Dental materials : official publication of the Academy of Dental Materials · 2014
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 5 countries.

J KimDepartment of Conservative Dentistry, School of Dentistry, Kyung Hee University, Seoul, Korea.
L Gu
L Breschi
L Tjäderhane
K K Choi
D H Pashley
F R Tay
Augusta University · USKyung Hee University · KROulu University Hospital · FISun Yat-sen University · CNUniversity of Trieste · IT

Funding

Biomimetic remineralization of resin-dentin bondsR21DE019213 · NIDCR · AUGUSTA UNIVERSITY · PI TAY, FRANKLIN CHI MENG · 2009 to 2010
$362k
NIDCR NIH HHS R21 DE019213NIDCR NIH HHS R21 DE019213-01
6 · The paper itself

Abstract

During mineralization, unbound water within the collagen matrix is replaced by apatite. This study tested the null hypothesis that there is no difference in the status of in vitro biomimetic remineralization of hybrid layers, regardless of their moisture contents. Acid-etched dentin was bonded with One-Step with ethanol-wet-bonding, water-wet-bonding, and water-overwet-bonding protocols. Composite-dentin slabs were subjected to remineralization for 1-4 months in a medium containing dual biomimetic analogs, with set Portland cement as the calcium source and characterized by transmission electron microscopy. Remineralization was either non-existent or restricted to the intrafibrillar mode in ethanol-wet-bonded specimens. Extensive intrafibrillar and interfibrillar remineralization was observed in water-wet-bonded specimens. Water-overwet specimens demonstrated partial remineralization of hybrid layers and precipitation of mineralized plates within water channels. The use of ethanol-wet-bonding substantiates that biomimetic remineralization is a progressive dehydration process that replaces residual water in hybrid layers with apatite crystallites.

Indexed as

Acid Etching, DentalAcrylic ResinsApatitesBiomimeticsCalciumChemical PrecipitationCollagenComposite ResinsDental BondingDental CementsDental MaterialsDentinDentin-Bonding AgentsEthanolHumansMaterials TestingAcrylic ResinsApatitesBis-GMA, BPDM, HEMA dental-bonding resinCalciumcarbopol 940CollagenComposite ResinsDental CementsDental MaterialsDentin-Bonding AgentsEpic TMPTEthanolMethacrylatesOrganophosphonatesPolyvinylsSolventsWater

Identifiers

PMID20200419
PMCPMC2873130
OpenAlexW1971422359

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.