ArticleAsia Pacific journal of clinical nutrition2010
High prevalence of low HDL-c in the Philippines compared to the US: population differences in associations with diet and BMI.
Article in Asia Pacific journal of clinical nutrition, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 25 citations in OpenAlex.
- Deriving sex-specific anthropometric cut-points for obesity and cardiovascular disease risk in Qatari adults.International journal of obesity (2005) · 2026Article
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- Comparison of cardiovascular disease risk factors among FiLWHEL (2014-2016), NNS (2013) and KNHANES (2013-2015) women.BMC women's health · 2023Article
- Prevalence of plasma lipid disorders with an emphasis on LDL cholesterol in selected countries in the Asia-Pacific region.Lipids in health and disease · 2021Review
- High prevalence of dyslipidaemia subtypes and their associated personal and clinical attributes in Malaysian adults: the REDISCOVER study.BMC cardiovascular disorders · 2021Article
- Cardiometabolic Risk Factors leading to Diabetes Mellitus among the Young (YOD) from the 8Journal of the ASEAN Federation of Endocrine Societies · 2021Article
- Clinical, Demographic, and Biochemical Characteristics of Patients with Acute ST-Segment Elevation Myocardial Infarction: An Analysis of Acute Coronary Syndrome Registry Data of a Single Medical Center from 2005 to 2016.Acta Cardiologica Sinica · 2020Article
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- Seventeen-Year Changes in Body Mass Index, Waist Circumference, Elevated Blood Pressure, and Diabetes Phenotypes in a Cohort of Filipino Women.Asia-Pacific journal of public health · 2018Article
- A Health Needs Assessment of the Filipino American Community in the Greater Las Vegas Area.Health equity · 2018Article
- Expert opinion on the applicability of dyslipidemia guidelines in Asia and the Middle East.International journal of general medicine · 2018Article
- Cardiovascular Disease Risk Score: Results from the Filipino-American Women Cardiovascular Study.Journal of racial and ethnic health disparities · 2017Article
- The High Prevalence of Low HDL-Cholesterol Levels and Dyslipidemia in Rural Populations in Northwestern China.PloS one · 2015Article
- Racial/ethnic differences in dyslipidemia patterns.Circulation · 2014Article
- Clustering and determinants of cardiometabolic risk factors among Filipino young adults.Asia Pacific journal of clinical nutrition · 2014Article
- Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.Journal of lipid research · 2013Article
- Characteristics of metabolic syndrome based on clustering pattern among Korean adolescents: findings from the Korean National Health and Nutrition Examination Survey, 2007-2008.European journal of pediatrics · 2013Article
- Cluster analysis reveals important determinants of cardiometabolic risk patterns in Filipino women.Asia Pacific journal of clinical nutrition · 2012Article
- Coconut oil is associated with a beneficial lipid profile in pre-menopausal women in the Philippines.Asia Pacific journal of clinical nutrition · 2011Article
- Pattern of dyslipidemia and associated factors in coronary artery disease patients in Khyber Pakhtunkhwa: A cross-sectional secondary data analysis.Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Cardiovascular disease (CVD) is a leading cause of death in the Philippines, although few studies here have examined the lipid profiles underlying disease risk. The isolated low high density lipoprotein cholesterol (HDL-c) phenotype has been implicated as a CVD risk factor, the prevalence of which exhibits significant variation across populations. To assess population variation in individual lipid components and their associations with diet and anthropometric characteristics, we compare lipid profiles in a population of adult Filipino women (n=1877) to US women participating in the National Health and Nutrition Examination Survey (NHANES, n=477). We conducted multiple regression models to assess the relationship between lipid components, body mass index, and dietary variables in the two populations. We measured the prevalence of lipid phenotypes, and logistic regression models determined the predictors of the isolated low HDL-c phenotype. High density lipoprotein cholesterol was lower in the Philippines (40.8+/-0.2 mg/dL) than in NHANES (60.7+/-0.7 mg/dL). The prevalence of the isolated low HDL-c phenotype was 28.8%, compared to 2.10% in NHANES. High prevalence among Filipinos was relatively invariant across all levels of BMI, but was strongly inversely related to BMI in NHANES and exhibited only at the BMI>25 kg/m2 threshold. Diet did not consistently predict the low-HDL phenotype in Filipinos. Filipino women exhibit a high prevalence of the isolated low HDL-c phenotype, which is largely decoupled from anthropometric factors. The relationship of CVD to population variation in dyslipidemia and body composition needs further study, particularly in populations where the burden of cardiovascular and metabolic disease is rapidly increasing.
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20199988PMC3152979W2146322686What OpenQuestion holds
Registered trials
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