ReviewSleep & breathing = Schlaf & Atmung2010
Inflammation accelerates atherosclerotic processes in obstructive sleep apnea syndrome (OSAS).
Review in Sleep & breathing = Schlaf & Atmung, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- A meta-analysis on the association between obstructive sleep apnea and periodontitis.Sleep & breathing = Schlaf & Atmung · 2023Pooled it
- Obstructive sleep apnea increases the risk of cardiac events after percutaneous coronary intervention: a meta-analysis of prospective cohort studies.Sleep & breathing = Schlaf & Atmung · 2018Pooled it
- Oxidative stress and inflammatory profiles in obstructive sleep apnea: are short-term CPAP or aerobic exercise therapies effective?Sleep & breathing = Schlaf & Atmung · 2020Trial
- Tongue Ultrasonography in the Screening of Severe Obstructive Sleep Apnea Syndrome-Promising Potential for Overloaded Sleep Centers.Diseases (Basel, Switzerland) · 2024Article
- Association of Tumor Necrosis Factor-Alpha, Interleukin-1β, Interleukin-8, and Interferon-γ with Obstructive Sleep Apnea in Both Children and Adults: A Meta-Analysis of 102 Articles.Journal of clinical medicine · 2024Review
- Mechanism of hypoxia-induced damage to the mechanical property in human erythrocytes-band 3 phosphorylation and sulfhydryl oxidation of membrane proteins.Frontiers in physiology · 2024Article
- Increased Levels of VCAM-1 in Patients with High Cardiovascular Risk and Obstructive Sleep Apnea Syndrome.Biomedicines · 2023Article
- Anemia and Hypoxia Impact on Chronic Kidney Disease Onset and Progression: Review and Updates.Cureus · 2023Review
- The molecular link between obstructive sleep apnea and osteoarthritis: based on bioinformatics analysis and experimental validation.American journal of translational research · 2023Article
- Article
- Hypoxia and Inflammation: Insights From High-Altitude Physiology.Frontiers in physiology · 2021Review
- Exposure to intermittent hypoxia inhibits allergic airway inflammation in a murine model of asthma.Sleep & breathing = Schlaf & Atmung · 2020Article
- Adherence to a Dietary Approach to Stop Hypertension (DASH)-Style in Relation to Daytime Sleepiness.Nature and science of sleep · 2020Article
- Effect of Social Factors and the Natural Environment on the Etiology and Pathogenesis of Diabetes Mellitus.International journal of endocrinology · 2019Review
- Does severe obstructive sleep apnea syndrome alter retrobulbar blood flow? A color Doppler ultrasound study.Journal of medical ultrasonics (2001) · 2018Article
- Risk of Nephrolithiasis in Patients With Sleep Apnea: A Population-Based Cohort Study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018Article
- Evaluation of the association between sleep apnea and polyunsaturated fatty acids profiles in patients after percutaneous coronary intervention.Heart and vessels · 2017Article
- Hypoxia: The Force that Drives Chronic Kidney Disease.Clinical medicine & research · 2016Review
- The role inflammatory response genes in obstructive sleep apnea syndrome: a review.Sleep & breathing = Schlaf & Atmung · 2016Review
- Inflammation induced by increased frequency of intermittent hypoxia is attenuated by tempol administration.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnea syndrome (OSAS) is an often underestimated sleep disorder that has been associated with cardiovascular disease. OSAS is characterized by cycles of apnea and/or hypopnea during sleep caused by the collapse of the upper airways. Intermittent hypoxia deriving from the cycles of apnea/arousals (to retrieve the ventilation) plays a pivotal role in the pathogenesis of the disease. Obesity is the most frequent predisposing condition of OSAS. Recent evidence suggests that OSAS could be considered as a pro-atherosclerotic disease, independently of visceral fat amount. Oxidative stress, cardiovascular inflammation, endothelial dysfunction, and metabolic abnormalities in OSAS could accelerate atherogenesis. The present review is focused on the possible pathophysiological mediators which could favor atherosclerosis in OSAS.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.