ArticleDigestive diseases and sciences2010
Quantification of the effects of the volume and viscosity of gastric contents on antral and fundic activity in the rat stomach maintained ex vivo.
Article in Digestive diseases and sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 40 citations in OpenAlex.
- Mapping the rat gastric slow-wave conduction pathway: bridging in vitro and in vivo methods, revealing a loosely coupled region in the distal stomach.American journal of physiology. Gastrointestinal and liver physiology · 2024Article
- Diffeomorphic Surface Modeling for MRI-Based Characterization of Gastric Anatomy and Motility.IEEE transactions on bio-medical engineering · 2023Article
- Evaluation of Pharmacobezoar Formation from Suspensions of Spray-Dried Amorphous Solid Dispersions: An MRI Study in Rats.Pharmaceutics · 2023Article
- An In Vitro Model to Investigate the Potential of Solid Dispersions to Form Pharmacobezoars.Pharmaceutics · 2022Article
- Organisation of the musculature of the rat stomach.Journal of anatomy · 2022Article
- Quantifying Patterns of Smooth Muscle Motility in the Gut and Other Organs With New Techniques of Video Spatiotemporal Mapping.Frontiers in physiology · 2018Article
- Melanocortin signaling in the brainstem influences vagal outflow to the stomach.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Fluid mechanical consequences of pendular activity, segmentation and pyloric outflow in the proximal duodenum of the rat and the guinea pig.Journal of the Royal Society, Interface · 2013Article
- Origin, propagation and regional characteristics of porcine gastric slow wave activity determined by high-resolution mapping.Neurogastroenterology and motility · 2010Article
- Luminal Cholera Toxin Alters Motility in Isolated Guinea-Pig Jejunum via a Pathway Independent of 5-HT(3) Receptors.Frontiers in neuroscience · 2010Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe aim of this study was to examine the effect of varying the rheological properties of perfusate on the volume and muscular activity of the various compartments of the rat stomach.
methodsImage analysis was used to quantify the activity of the ex vivo stomach preparations when perfused according to a ramp profile.
resultsThe area of the fundus increased to a greater extent than that of the body when watery or viscous material was perfused. However, initial distension of the corpus was greater and occurred more rapidly when viscous material was perfused. Only the fundus expanded when perfusion followed the administration of verapamil. The frequency of antrocorporal contractions decreased significantly and the amplitude of antrocorporal contractions increased significantly with increase in gastric volume. The velocity of antrocorporal contractions did not vary with gastric volume but varied regionally in some preparations being faster distally than proximally. Neither the frequency, amplitude or velocity of antrocorporal contractions differed when pseudoplastic rather than watery fluid was perfused. However, the characteristics of antrocorporal contractions changed significantly when the stomach was perfused with material with rheological characteristics that induce different patterns of wall tension to those normally encountered. Hence, the mean frequency and speed of propagation of antrocorporal contractions increased and their direction of propagation became inconstant.
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