ArticleFrontiers in neuroscience2009
Micropatterned substrates for studying astrocytes in culture.
Article in Frontiers in neuroscience, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Astrocytes increase ATP exocytosis mediated calcium signaling in response to microgroove structures.Scientific reports · 2015Article
- Astrocytes revisited: concise historic outlook on glutamate homeostasis and signaling.Croatian medical journal · 2012Review
- Temporal characteristics of vesicular fusion in astrocytes: examination of synaptobrevin 2-laden vesicles at single vesicle resolution.The Journal of physiology · 2011Article
- Engineering skeletal muscle tissue--new perspectives in vitro and in vivo.Journal of cellular and molecular medicine · 2010Review
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2 authors.
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Abstract
Recent studies of the physiological roles of astrocytes have ignited renewed interest in the functional significance of these glial cells in the central nervous system. Many of the newly discovered astrocytic functions were initially demonstrated and characterized in cell culture systems. We discuss the use of microculture techniques and micropatterning of cell-adhesive substrates in studies of astrocytic Ca(2+) excitability and bidirectional neuron-astrocyte signaling. This culturing approach aims to reduce the level of complexity of the system by limiting the interacting partners and by controlling the localization of cells. It provides tight control over experimental conditions allowing detailed characterization of cellular functions and intercellular communication. Although such a reductionist approach yields some difference in observations between astrocytic properties in culture and in situ, general phenomena discovered in cell culture systems, however, have also been found in vivo.
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