Trial reportOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2011
Dose-response effect of 40 weeks of resistance training on bone mineral density in older adults.
Trial report in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- The effects of exercise interventions on depressive symptoms in stroke patients: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Effects of exercise based on ACSM recommendations on bone mineral density in individuals with osteoporosis: a systematic review and meta-analyses of randomized controlled trials.Frontiers in physiology · 2023Pooled it
- Effects of different exercise intensity on bone mineral density in adults: a comparative systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Pooled it
- Impact of high-load resistance training on bone mineral density in osteoporosis and osteopenia: a meta-analysis.Journal of bone and mineral metabolism · 2021Pooled it
- Evidence on physical activity and osteoporosis prevention for people aged 65+ years: a systematic review to inform the WHO guidelines on physical activity and sedentary behaviour.The international journal of behavioral nutrition and physical activity · 2020Pooled it
- Effects of dynamic resistance exercise on bone mineral density in postmenopausal women: a systematic review and meta-analysis with special emphasis on exercise parameters.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Pooled it
- The effect of OsteoStrong compared to dynamic multicomponent exercise on bone strength in older women: the BONEMORE non-inferiority randomized controlled trial.Archives of osteoporosis · 2026Trial
- Effect of six weeks of resistance training on bone preservation in older adults: a randomized control trial.Aging clinical and experimental research · 2023Trial
- Immediate versus delayed exercise in men initiating androgen deprivation: effects on bone density and soft tissue composition.BJU international · 2019Trial
- Epigenetic changes in leukocytes after 8 weeks of resistance exercise training.European journal of applied physiology · 2016Trial
- Trial
- The benefits of a high-intensity aquatic exercise program (HydrOS) for bone metabolism and bone mass of postmenopausal women.Journal of bone and mineral metabolism · 2014Trial
- Does frequency of resistance training affect tibial cortical bone density in older women? A randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013Trial
- Optimal Resistance Exercise Strategies for Improving Bone Mineral Density in Middle-Aged and Older Adults: A Network Meta-Analysis Based on Exercise Intensity and Frequency.Calcified tissue international · 2026Article
- Surface Electromyography-Based Evaluation of Neuromuscular Recruitment Under Different Resistance Conditions During Water-Resistance Rowing.Sensors (Basel, Switzerland) · 2026Article
- Bone Mineral Density Findings Add Limited Novelty to Prior Meta-Analyses: A Comment on Shen Et al.Geriatrics & gerontology international · 2026Article
- Dose-dependent effects of flavanol-rich dark chocolate intake before resistance exercise on arterial stiffness in healthy young men.European journal of applied physiology · 2026Article
- Review
- Acute effect of dark chocolate intake before high-intensity resistance exercise on arterial stiffness in healthy young men.Journal of exercise science and fitness · 2025Article
- Synergistic Effects of an Eight-Week Resistance Training and Probiotic Supplementation on Bone Metabolism in Ovariectomized Rats.Preventive nutrition and food science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledResistance training is becoming popular for maintaining bone health. Previous studies examined high intensity exercise; we compared high and low intensity resistance training performed 2 or 3 days per week in older adults. We found positive bone density responses for the hip and spine for all types of resistance training.
introductionThis study determined the dose-response effect of resistance training on lumbar spine, proximal femur, and total body bone mineral density (BMD) in older men and women (55-74 years).
methodsSubjects included 45 men and 79 women who were assigned to one of the following training groups: 1-high intensity (80% 1RM), 2 days/week (2HI); 2-low intensity (40% 1RM), 2 days/week (2LI); 3-high intensity (80% 1RM), 3 days/week (3HI); and 4-low intensity (40% 1RM), 3 days/week (3LI). Bone scans (dual energy X-ray absorptiometry) were performed at baseline and after 40 weeks of training. Muscular strength (1-repetition maximum) was assessed every 5 weeks.
resultsThere were significant trial (p < 0.05) effects but no significant trial × training group interactions for the BMD sites. Spine, trochanter, and total hip BMD increased from baseline to 40 weeks; however, the total body BMD site decreased in the 3LI group. Men and women exhibited similar improvements for the trochanter and total hip sites but the percent change in the spine tended (p = 0.054) to be higher for men (1.8%) than women (0.4%).
conclusionsThe resistance training programs, regardless of intensity and frequency, were effective in improving BMD of the proximal femur and lumbar spine but not the total body. Both men and women responded similarly for the hip sites but men show a greater response at the lumbar spine than women.
Indexed as
Identifiers
20195844What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.