Evidence map›Paper›PMID 20195672›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2010

The rag locus of Porphyromonas gingivalis might arise from Bacteroides via horizontal gene transfer.

Z Su, F Kong, S Wang, J Chen, R Yin, C Zhou, Y Zhang, Z He, Y Shi, Y Xue and 4 more

Abstract read
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Prevalence and Phylogenetic Analysis of Lipoprotein-GeneAntibiotics (Basel, Switzerland) · 2023
    Article
  2. Review
  3. Article
  4. Review
  5. Genetic exchange and reassignment inJournal of oral microbiology · 2018
    Review
  6. Article
  7. Article
  8. Detection of periodontal pathogens in newborns and children with mixed dentition.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Z SuDepartment of Immunology and Laboratory Immunology, Center of Medical Laboratory, Jiangsu University, Zhenjiang, China.
F Kong
S Wang
J Chen
R Yin
C Zhou
Y Zhang
Z He
Y Shi
Y Xue
X Shi
L Lu
Q Shao
H Xu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porphyromonas gingivalis is regarded as one of the risk factors of periodontitis. P. gingivalis exhibits a wide variety of genotypes. Many insertion sequences (ISs), located in their chromosomes, made P. gingivalis differentiate into virulent and avirulent strains. In this research, we investigated the prevalence of P. gingivalis in the gingival crevicular fluid (GCF) among periodontitis patients from Zhenjiang, China, detected the P. gingivalis rag locus distributions by multiplex polymerase chain reaction (PCR), and analyzed the origin of the P. gingivalis rag locus based on evolution. There were three rag locus variants co-existing in Zhenjiang. The results showed that the rag locus may be associated with severe periodontitis. This work also firstly ascertained that the rag locus might arise, in theory, from Bacteroides sp. via horizontal gene transfer.

Indexed as

Evolution, MolecularGene Transfer, HorizontalAdolescentAdultAgedAmino Acid SequenceBacteroidesChinaCluster AnalysisDNA, BacterialFemaleGenes, BacterialHumansMaleMiddle AgedMolecular Sequence DataDNA, Bacterial

Identifiers

PMID20195672
PMCPMC2953623

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.