ArticleChromosoma2010
Development and analysis of a germline BAC resource for the sea lamprey, a vertebrate that undergoes substantial chromatin diminution.
Article in Chromosoma, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Extensive DNA methylome rearrangement during early lamprey embryogenesis.Nature communications · 2024Article
- Novel selectively amplified DNA sequences in the germline genome of the Japanese hagfish, Eptatretus burgeri.Scientific reports · 2022Article
- Why Do Some Vertebrates Have Microchromosomes?Cells · 2021Review
- Reconstruction of proto-vertebrate, proto-cyclostome and proto-gnathostome genomes provides new insights into early vertebrate evolution.Nature communications · 2021Article
- Programmed DNA Elimination in Vertebrates.Annual review of animal biosciences · 2021Review
- The genome sequence of the channel bull blenny,Wellcome open research · 2020Article
- Germline-Specific Repetitive Elements in Programmatically Eliminated Chromosomes of the Sea Lamprey (Genes · 2019Article
- The sea lamprey germline genome provides insights into programmed genome rearrangement and vertebrate evolution.Nature genetics · 2018Article
- Molecular cytogenetic characterization of chromosome site-specific repetitive sequences in the Arctic lamprey (Lethenteron camtschaticum, Petromyzontidae).DNA research : an international journal for rapid publication of reports on genes and genomes · 2017Article
- Discovery of large genomic inversions using long range information.BMC genomics · 2017Article
- Characterization of Somatically-Eliminated Genes During Development of the Sea Lamprey (Petromyzon marinus).Molecular biology and evolution · 2016Article
- Cellular and Molecular Features of Developmentally Programmed Genome Rearrangement in a Vertebrate (Sea Lamprey: Petromyzon marinus).PLoS genetics · 2016Article
- Article
- Lampreys as Diverse Model Organisms in the Genomics Era.Bioscience · 2015Article
- The sea lamprey meiotic map improves resolution of ancient vertebrate genome duplications.Genome research · 2015Article
- Genome-wide analysis of the ATP-binding cassette (ABC) transporter gene family in sea lamprey and Japanese lamprey.BMC genomics · 2015Article
- Article
- Palindromic GOLGA8 core duplicons promote chromosome 15q13.3 microdeletion and evolutionary instability.Nature genetics · 2014Article
- Programmed DNA elimination in multicellular organisms.Current opinion in genetics & development · 2014Review
- Insight from the lamprey genome: glimpsing early vertebrate development via neuroendocrine-associated genes and shared synteny of gonadotropin-releasing hormone (GnRH).General and comparative endocrinology · 2013Article
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Authors and funding
5 authors.
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Abstract
Over the last several years, the sea lamprey (Petromyzon marinus) has grown substantially as a model for understanding the evolutionary fundaments and capacity of vertebrate developmental and genome biology. Recent work on the lamprey genome has resulted in a preliminary assembly of the lamprey genome and led to the realization that nearly all somatic cell lineages undergo extensive programmed rearrangements. Here we describe the development of a bacterial artificial chromosome (BAC) resource for lamprey germline DNA and use sequence information from this resource to probe the subchromosomal structure of the lamprey genome. The arrayed germline BAC library represents approximately 10x coverage of the lamprey genome. Analyses of BAC-end sequences reveal that the lamprey genome possesses a high content of repetitive sequences (relative to human), which show strong clustering at the subchromosomal level. This pattern is not unexpected given that the sea lamprey genome is dispersed across a large number of chromosomes (n approximately 99) and suggests a low-copy DNA targeting strategy for efficiently generating informative paired-BAC-end linkages from highly repetitive genomes. This library therefore represents a new and biologically informed resource for understanding the structure of the lamprey genome and the biology of programmed genome rearrangement.
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