ArticlePLoS computational biology2010
Spatial simulations of myxobacterial development.
Article in PLoS computational biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Ecological drivers of division of labour in Streptomyces.Current opinion in microbiology · 2022Review
- Flagellar Motor Transformed: Biophysical Perspectives of theFrontiers in microbiology · 2022Article
- Formation, collective motion, and merging of macroscopic bacterial aggregates.PLoS computational biology · 2022Article
- The environment topography alters the way to multicellularity inScience advances · 2021Article
- Interplay of mesoscale physics and agent-like behaviors in the parallel evolution of aggregative multicellularity.EvoDevo · 2020Review
- Data-driven modeling reveals cell behaviors controlling self-organization duringProceedings of the National Academy of Sciences of the United States of America · 2017Article
- Modeling evolution of spatially distributed bacterial communities: a simulation with the haploid evolutionary constructor.BMC evolutionary biology · 2015Article
- Bacterial stigmergy: an organising principle of multicellular collective behaviours of bacteria.Scientifica · 2015Review
- Development of cell differentiation in the transition to multicellularity: a dynamical modeling approach.Frontiers in microbiology · 2015Article
- Nutrient-regulated proteolysis of MrpC halts expression of genes important for commitment to sporulation during Myxococcus xanthus development.Journal of bacteriology · 2014Article
- Self-organization of bacterial biofilms is facilitated by extracellular DNA.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Pattern-formation mechanisms in motility mutants of Myxococcus xanthus.Interface focus · 2012Article
- Quantifying aggregation dynamics during Myxococcus xanthus development.Journal of bacteriology · 2011Article
- Statistical image analysis reveals features affecting fates of Myxococcus xanthus developmental aggregates.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Experimentally guided computational model discovers important elements for social behavior in myxobacteria.PloS one · 2011Article
- Mathematical description of bacterial traveling pulses.PLoS computational biology · 2010Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many bacteria exhibit multicellular behaviour, with individuals within a colony coordinating their actions for communal benefit. One example of complex multicellular phenotypes is myxobacterial fruiting body formation, where thousands of cells aggregate into large three-dimensional structures, within which sporulation occurs. Here we describe a novel theoretical model, which uses Monte Carlo dynamics to simulate and explain multicellular development. The model captures multiple behaviours observed during fruiting, including the spontaneous formation of aggregation centres and the formation and dissolution of fruiting bodies. We show that a small number of physical properties in the model is sufficient to explain the most frequently documented population-level behaviours observed during development in Myxococcus xanthus.
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