Evidence map›Paper›PMID 20194697›Full record

ArticleAntimicrobial agents and chemotherapy2010

Synergistic activities of three triazoles with caspofungin against Candida glabrata isolates determined by time-kill, Etest, and disk diffusion methods.

Nuri Kiraz, Ilknur Dag, Mustafa Yamac, Abdurrahman Kiremitci, Nilgun Kasifoglu, Yasemin Oz

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

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  10. Plant-derived antifungal agent poacic acid targets β-1,3-glucan.Proceedings of the National Academy of Sciences of the United States of America · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Nuri KirazDepartment of Microbiology, Medical Faculty, University of Eskisehir Osmangazi, Eskisehir, Turkey. nkiraz@ogu.edu.tr
Ilknur Dag
Mustafa Yamac
Abdurrahman Kiremitci
Nilgun Kasifoglu
Yasemin Oz
Artistic Realization Technologies · USEskişehir Osmangazi University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combinations of voriconazole, fluconazole, and itraconazole with caspofungin were evaluated against 50 Candida glabrata isolates by the time-kill, disk diffusion, and Etest methods. The majority of antifungal combinations were indifferent. By the time-kill method, synergistic activity was detected with eight (16%) of the caspofungin-voriconazole and seven (14%) of the caspofungin-fluconazole combinations, but synergy was not seen with the caspofungin-itraconazole combination. Further comparisons of the Etest and disk diffusion synergy techniques with the time-kill method are warranted.

Indexed as

Antifungal AgentsCandida glabrataCaspofunginDisk Diffusion Antimicrobial TestsDrug Resistance, FungalDrug SynergismEchinocandinsEndpoint DeterminationFluconazoleItraconazoleLipopeptidesPyrimidinesTime FactorsTriazolesVoriconazoleAntifungal AgentsCaspofunginEchinocandinsFluconazoleItraconazoleLipopeptidesPyrimidinesTriazolesVoriconazole

Identifiers

PMID20194697
PMCPMC2863687
OpenAlexW2152086223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.