ReviewThe Journal of bone and joint surgery. American volume2010
The assessment of fracture risk.
Review in The Journal of bone and joint surgery. American volume, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 153 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
153 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Opportunistic CT-based osteoporosis screening of the hip: a systematic review of diagnostic accuracy.Archives of orthopaedic and trauma surgery · 2025Pooled it
- Osteoporosis drug therapy strategies in the setting of disease-modifying agents for autoimmune disease.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013Pooled it
- Trial
- Prediction of Fracture Risk From Early-Stage Bone Markers in Patients With Osteoporosis Treated With Once-Yearly Administered Zoledronic Acid.Journal of clinical pharmacology · 2021Trial
- Modeling and simulation of bone mineral density in Japanese osteoporosis patients treated with zoledronic acid using tartrate-resistant acid phosphatase 5b, a bone resorption marker.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Trial
- Cortical indices, DXA, and FRAX as indicators of bone fragility: a comparative human cadaveric study.JBMR plus · 2026Article
- Associations between SARC-F score and FRAX score in patients with rheumatoid arthritis: A cross-sectional study.Clinical rheumatology · 2026Article
- [Diagnosis of osteoporosis-importance of dual-energy X-ray absorptiometry].Orthopadie (Heidelberg, Germany) · 2026Review
- Bone health in gender-diverse individuals: current challenges and future directions.Hormones (Athens, Greece) · 2026Review
- Edentulism and incident hip fracture among middle-aged and older adults in China: evidence from the CHARLS.BMC public health · 2026Article
- Comparative Assessment of Proximal Humeral Bone Density Using CT Osteoabsorptiometry, Bone Microarchitecture Analysis, and a HU-Based Calibration Method: A CT and Micro-CT Study in Elderly Body Donors (65-86 Years).Diagnostics (Basel, Switzerland) · 2026Article
- The prospective association between high-density lipoprotein (HDL) cholesterol and risk of incident fractures in the general population.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Concordance of the Fracture Risk Assessment Tool With and Without Bone Mineral Density and Its Role in Predicting Postoperative Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery.Neurosurgery practice · 2025Article
- [Diagnosis of osteoporosis-importance of dual-energy X-ray absorptiometry].Zeitschrift fur Rheumatologie · 2025Review
- Prophylactic fixation in elderly fractures: Preventive breakthrough or unnecessary intervention?World journal of orthopedics · 2025Review
- Bone Health in Space Flight: Incomplete Bone Mineral Density Convalescence at 1 Year Postmission Without Increased Fracture Risk.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Loss of intraflagellar transport 140 in osteoblasts cripples bone fracture healing.Fundamental research · 2025Article
- Potentially inappropriate polypharmacy is an important predictor of 30-day emergency hospitalisation in older adults: a machine learning feature validation study.Age and ageing · 2025Article
- Evolving strategies for osteoporosis management in postmenopausal women: From tradition to innovation.Medicine · 2025Review
- The Multifactorial Relationship Between Bone Tissue Water and Stiffness at the Proximal Femur.Calcified tissue international · 2025Article
93 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Bone mineral density is considered to be the standard measure for the diagnosis of osteoporosis and the assessment of fracture risk. The majority of fragility fractures occur in patients with bone mineral density in the osteopenic range. The Fracture Risk Assessment Tool (FRAX) can be used as an assessment modality for the prediction of fractures on the basis of clinical risk factors, with or without the use of femoral neck bone mineral density. Treatment of osteoporosis should be considered for patients with low bone mineral density (a T-score of between -1.0 and -2.5) as well as a ten-year risk of hip fracture of > or = 3% or a ten-year risk of a major osteoporosis-related fracture of > or = 20% as assessed with the FRAX. Biochemical bone markers are useful for monitoring the efficacy of antiresorptive or anabolic therapy and may aid in identifying patients who have a high risk of fracture. An approach combining the assessment of bone mineral density, clinical risk factors for fracture with use of the FRAX, and bone turnover markers will improve the prediction of fracture risk and enhance the evaluation of patients with osteoporosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.