Trial reportJournal of alternative and complementary medicine (New York, N.Y.)2010
A pilot study of chromium picolinate for weight loss.
Trial report in Journal of alternative and complementary medicine (New York, N.Y.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- The effects of chromium supplementation on blood pressure: a systematic review and meta-analysis of randomized clinical trials.European journal of clinical nutrition · 2022Pooled it
- A Systematic Review of Dietary Supplements and Alternative Therapies for Weight Loss.Obesity (Silver Spring, Md.) · 2021Pooled it
- Chromium picolinate supplementation for overweight or obese adults.The Cochrane database of systematic reviews · 2013Pooled it
- A double-blind, randomized pilot trial of chromium picolinate for binge eating disorder: results of the Binge Eating and Chromium (BEACh) study.Journal of psychosomatic research · 2013Trial
- Chromium effects on glucose tolerance and insulin sensitivity in persons at risk for diabetes mellitus.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical EndocrinologistsTrial
- A novel "turn-on" fluorescence probe for chromium(III) sensing: experimental validation and theoretical insights.Journal of molecular modeling · 2026Article
- Toxic Metals Content in Impacted Third Molars and Adjacent Bone Tissue in Different Groups of Patients.Materials (Basel, Switzerland) · 2021Article
- The Possibilities of Using Chromium Salts as an Agent Supporting Treatment of Polycystic Ovary Syndrome.Biological trace element research · 2019Review
- Scientific Opinion on Dietary Reference Values for chromium.EFSA journal. European Food Safety Authority · 2014Article
- High frequency of serum chromium deficiency and association of chromium with triglyceride and cholesterol concentrations in patients awaiting bariatric surgery.Obesity surgery · 2014Article
- Article
- Chromium Picolinate for the Prevention of Type 2 Diabetes.Treatment strategies. Diabetes · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundChromium is an essential trace element and nutritional supplement that has garnered interest for use as a weight loss aid.
objectiveThis trial assesses the effects of chromium picolinate supplementation, alone and combined with nutritional education, on weight loss in apparently healthy overweight adults.
designThis was a randomized, double-blind, placebo-controlled trial of 80 otherwise healthy, overweight adults assessed at baseline for central adiposity measured by computerized tomography. Subjects were randomly assigned to daily ingestion of 1000 microg of chromium picolinate or placebo for 24 weeks. All subjects received passive nutritional education at the 12-week point in both the intervention and control groups. Outcomes include weight, height, blood pressure, percent body fat, serum, and urinary biomarkers.
resultsAt baseline, both the chromium and placebo groups had similar mean body mass index (BMI) (chromium = 36 +/- 6.7 kg/m(2) versus placebo = 36.1 +/- 7.6 kg/m(2); p = 0.98). After 12 weeks, no change was seen in BMI in the intervention as compared to placebo (chromium = 0.3 +/- 0.8 kg/m(2) versus placebo = 0.0 +/- 0.4 kg/m(2); p = 0.07). No change was seen in BMI after 24 weeks in the intervention as compared to placebo (chromium = 0.1 +/- 0.2 kg/m(2) versus placebo = 0.0 +/- 0.5 kg/m(2); p = 0.81). Variation in central adiposity did not affect any outcome measures.
conclusionsSupplementation of 1000 microg of chromium picolinate alone, and in combination with nutritional education, did not affect weight loss in this population of overweight adults. Response to chromium did not vary with central adiposity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.