ArticleInternational ophthalmology2010
Clinical features of pediatric Graves' orbitopathy.
Article in International ophthalmology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Thyroid eye disease in paediatric Graves' disease: a case series from the Gulf region with comparison to adults.International ophthalmology · 2026Article
- Pediatric graves' orbitopathy: a case series of 136 Chinese patients.International ophthalmology · 2025Article
- Efficacy of Tocilizumab in Refractory Graves Orbitopathy From Real-World Clinical Practice: An Observational Study.Journal of the Endocrine Society · 2024Article
- Graves' Orbitopathy: Report of 82 cases.La Tunisie medicale · 2021Article
- [Role and effectiveness of radioactive-iodine therapy for the treatment of Grave's disease].The Pan African medical journal · 2020Article
- Incidence and clinical characteristics of pediatric eyelid retraction.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2019Article
- Predictive Factors of Development of Graves' Ophthalmopathy for Patients with Juvenile Graves' Disease.International journal of endocrinology · 2016Article
- Age differences in clinical manifestation and prognosis of thyroid eye disease.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2015Article
- Assessment of visual acuity, refraction changes, and proptosis in different ages of patients with thyroid diseases.International journal of endocrinology · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pediatric Graves' orbitopathy is rare, thus its clinical picture is less well defined in comparison with the adult population. Therefore it is our aim to describe the clinical spectrum at our tertiary referral center. We identified 11 patients under the age of 18 years (3♂, 8♀; range 3-16 years, mean age 14.5 years) with Graves' disease and signs of orbitopathy. Seven of them where reevaluated (mean follow-up 25 months, range 3-66 months). Eyelid retraction and proptosis were the predominant signs in 10/11 of our patients. In six patients, Hertel readings ranged from 22 mm or above. Mild ocular motility impairment was seen in four children. Active orbitopathy or severe impairment of visual acuity/ocular motility, corneal or optic nerve involvement was not observed in our study. Our series confirms that pediatric Graves' orbitopathy lacks significant inflammatory features; however, proptosis is common and may be marked. All seven patients who were reevaluated did not show any clinically significant change of ocular signs during the observation period. In particular, there was no improvement of proptosis despite restoration of euthyroidism.
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