Evidence map›Paper›PMID 20190955›Full record

ArticleCurrent genomics2009

Hidden Markov Models and their Applications in Biological Sequence Analysis.

Byung-Jun Yoon

Abstract read
In one paragraph

Article in Current genomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Evolution, Mechanisms, and Therapeutic Implications of Mobile Tetracycline Destructases.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
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  8. An Integrative Variant Scoring Function for Finding Novel Genes Associated with Ovarian and Thyroid Cancer.International journal of environmental research and public health · 2026
    Article
  9. Article
  10. Review
  11. Review
  12. Early Sound-Based Meal Onset Detection Using Hidden Markov Models (HMMs).IEEE journal of translational engineering in health and medicine · 2026
    Article
  13. Article
  14. Article
  15. In Silico Identification and Molecular Characterization ofAntibiotics (Basel, Switzerland) · 2025
    Article
  16. Article
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  18. Genomic Insights into Emerging Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
  19. Article
  20. The Environment-Dependent Regulatory Landscape of thebioRxiv : the preprint server for biology · 2025
    Article

61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Byung-Jun YoonDepartment of Electrical & Computer Engineering, Texas A&M University, College Station, TX 77843-3128, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hidden Markov models (HMMs) have been extensively used in biological sequence analysis. In this paper, we give a tutorial review of HMMs and their applications in a variety of problems in molecular biology. We especially focus on three types of HMMs: the profile-HMMs, pair-HMMs, and context-sensitive HMMs. We show how these HMMs can be used to solve various sequence analysis problems, such as pairwise and multiple sequence alignments, gene annotation, classification, similarity search, and many others.

Indexed as

context-sensitive HMM (csHMM)Hidden Markov model (HMM)pair-HMMprofile-csHMMprofile-HMMsequence analysis.

Identifiers

PMID20190955
PMCPMC2766791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.