ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2009
Clinical presentation, diagnosis and management of Cryptococcus gattii cases: Lessons learned from British Columbia.
Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Geographical distribution of the Cryptococcus gattii species complex: a systematic review.The Lancet. Microbe · 2024Pooled it
- Adrenal Corticosteroids and Increased Intracranial Pressure in Nonimmunocompromised Patients With Cryptococcal Meningitis.The Journal of infectious diseases · 2026Article
- Cryptococcal Meningitis: Differences between Patients with and without HIV-Infection.Pathogens (Basel, Switzerland) · 2023Article
- Successful Isavuconazole Salvage Therapy for a Cryptococcus deuterogattii (AFLP6/VGII) Disseminated Infection in a European Immunocompetent Patient.Mycopathologia · 2021Article
- False-Negative CSF Cryptococcal Antigen withCase reports in infectious diseases · 2020Article
- Central Nervous System Cryptococcal Infections in Non-HIV Infected Patients.Journal of fungi (Basel, Switzerland) · 2019Review
- Epidemiological, Clinical and Outcome Aspects of Patients with Cryptococcosis Caused by Cryptococcus gattii from a Non-endemic Area of Brazil.Mycopathologia · 2019Article
- Dectin-3 Recognizes Glucuronoxylomannan ofFrontiers in immunology · 2018Article
- Adaptive Immunity toJournal of fungi (Basel, Switzerland) · 2017Article
- Management of Cryptococcus gattii meningoencephalitis.The Lancet. Infectious diseases · 2015Review
- Design, synthesis, and biological evaluation of aminothiazole derivatives against the fungal pathogens Histoplasma capsulatum and Cryptococcus neoformans.Bioorganic & medicinal chemistry · 2015Article
- Evasion of Innate Immune Responses by the Highly Virulent Cryptococcus gattii by Altering Capsule Glucuronoxylomannan Structure.Frontiers in cellular and infection microbiology · 2015Article
- Cryptococcus gattii infections.Clinical microbiology reviews · 2014Review
- Unusual sojourn of not-so-unusual pathogens.Lung India : official organ of Indian Chest Society · 2014Article
- Altered immune response differentially enhances susceptibility to Cryptococcus neoformans and Cryptococcus gattii infection in mice expressing the HIV-1 transgene.Infection and immunity · 2013Article
- Cryptococcus gattii in the United States: genotypic diversity of human and veterinary isolates.PloS one · 2013Article
- Recognition and diagnosis of Cryptococcus gattii infections in the United States.Emerging infectious diseases · 2012Article
- Cryptococcus gattii comparative genomics and transcriptomics: a NIH/NIAID White Paper.Mycopathologia · 2012Review
- Article
- Process analysis of variables for standardization of antifungal susceptibility testing of nonfermentative yeasts.Antimicrobial agents and chemotherapy · 2011Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The environmental fungus Cryptococcus gattii emerged on Vancouver Island, British Columbia (BC), in 1999. By the end of 2006, it led to 176 cases and eight deaths - one of the highest burdens of C gattii disease worldwide. The present paper describes three cases, and the BC experience in the diagnosis and management of this infection. All three cases presented with pulmonary findings, including cryptococcomas and infiltrates. One also presented with brain cryptococcomas. Cases were diagnosed by chest and brain imaging, and laboratory evidence including serum or cerebrospinal fluid cryptococcal antigen detection and culture of respiratory or cerebrospinal fluid specimens. Genotyping of fungal isolates confirmed infection with C gattii VGIIa. Pulmonary cases were treated with fluconazole. One patient with central nervous system disease was treated with amphotericin B followed by fluconazole. Although this infection remains rare, clinicians should be aware of it in patients with a compatible clinical presentation who are either living in or returning from a trip to BC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.