Evidence map›Paper›PMID 20190671›Full record

ReviewOptometry and vision science : official publication of the American Academy of Optometry2010

Pathogenesis of contact lens-associated microbial keratitis.

Suzanne M J Fleiszig, David J Evans

Abstract readReview
In one paragraph

Review in Optometry and vision science : official publication of the American Academy of Optometry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Orthokeratology lens-relatedThe Journal of international medical research · 2021
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Scleral lenses and PROSE: indications, complications, and future challenges.Medical hypothesis, discovery & innovation ophthalmology journal · 2025
    Review
  8. Bacterial contamination in contact lens training area in private optical clinics.Journal of ophthalmic inflammation and infection · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. BMJ case reports · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Suzanne M J FleiszigSchool of Optometry and Graduate Programs in Vision Science, Microbiology, Infectious Disease and Immunity, and Health and Medical Sciences, University of California-Berkeley, Berkeley, CA, USA. fleiszig@berkeley.edu
David J Evans

Funding

SIGNIFICANCE OF CORNEAL CELL INVASION BY BACTERIAR01EY011221 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI Suzanne MJ FLEISZIG · 1995 to 2026
$8.4M
INTRACELLULAR LIFESTYLE OF PSEUDOMONAS AERUGINOSAR01AI079192 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI FLEISZIG, SUZANNE MJ · 2009 to 2013
$2.0M
NEI NIH HHS EY011221NEI NIH HHS R01 EY011221NIAID NIH HHS AI079192NIAID NIH HHS R01 AI079192
6 · The paper itself

Abstract

Sight-threatening microbial keratitis associated with contact lens wear remains a serious concern for patients, eye-care practitioners, and the contact lens industry. Several decades of research and some major advances in lens and solution technology have not resulted in a decline in disease incidence. Here, we offer a perspective on the complex pathogenesis of microbial keratitis, the factors that have prevented a better understanding of this disease, and new approaches being used to tackle this important clinical problem.

Indexed as

AnimalsBacteriaContact LensesCorneaEye Infections, BacterialHumansKeratitisRisk Factors

Identifiers

PMID20190671
PMCPMC4379041

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.