ReviewWomen's health (London, England)2010
Development of pulmonary arterial hypertension in women: interplay of sex hormones and pulmonary vascular disease.
Review in Women's health (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 42 citations in OpenAlex.
- Trial
- Sex Differences in Impacts of Early Gestational and Peri-Adolescent Ozone Exposure on Lung Development in Rats: Implications for Later Life Disease in Humans.The American journal of pathology · 2024Article
- Pulmonary hypertension and insulin resistance: a mechanistic overview.Frontiers in endocrinology · 2023Review
- Newer insights into the pathobiological and pharmacological basis of the sex disparity in patients with pulmonary arterial hypertension.American journal of physiology. Lung cellular and molecular physiology · 2021Review
- Gender Difference in Damage-Mediated Signaling Contributes to Pulmonary Arterial Hypertension.Antioxidants & redox signaling · 2019Article
- The Homeodomain Transcription Factor NKX3.1 Modulates Bladder Outlet Obstruction Induced Fibrosis in Mice.Frontiers in pediatrics · 2019Article
- Sex-specific cardiopulmonary exercise testing parameters as predictors in patients with idiopathic pulmonary arterial hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
- Elevated microRNA-135a is associated with pulmonary arterial hypertension in experimental mouse model.Oncotarget · 2017Article
- Sex-specific cardiopulmonary exercise testing indices related to hemodynamics in idiopathic pulmonary arterial hypertension.Therapeutic advances in respiratory disease · 2017Article
- Cyp2c44 gene disruption exacerbated pulmonary hypertension and heart failure in female but not male mice.Pulmonary circulation · 2016Article
- The sexual dimorphism associated with pulmonary hypertension corresponds to a fibrotic phenotype.Pulmonary circulation · 2015Article
- Article
- Pulmonary artery pressure, gender, menopause, and pregnancy in schistosomiasis-associated pulmonary hypertension.Arquivos brasileiros de cardiologia · 2013Article
- Estrogen paradox in pulmonary hypertension: current controversies and future perspectives.American journal of respiratory and critical care medicine · 2012Review
- Ovarian stimulation and embryo banking for fertility preservation in a woman with severe mixed connective tissue disease: Is it safe?Journal of assisted reproduction and genetics · 2012Review
- Sex differences and sex steroids in lung health and disease.Endocrine reviews · 2012Review
- Estrogen rescues preexisting severe pulmonary hypertension in rats.American journal of respiratory and critical care medicine · 2011Article
- Kinetics of skeletal muscle O2 delivery and utilization at the onset of heavy-intensity exercise in pulmonary arterial hypertension.European journal of applied physiology · 2011Article
- Metabolic and hormonal derangements in pulmonary hypertension: from mouse to man.International journal of clinical practice. Supplement · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Pulmonary arterial hypertension (PAH) is a progressive disease of the pulmonary vasculature, ultimately resulting in right heart failure and death. This disease is strongly predominant in females, although little is known regarding how sex influences disease development. Recent developments highlighting the importance of estrogen metabolites in both animal models and human disease have substantially increased our understanding of PAH in women. This review will focus on general knowledge of PAH, translational and basic science data regarding sex hormones in the pulmonary vasculature and on clinical issues that are particular to women with PAH. Future directions for study include the influence of sex hormones on right ventricular responses, improving the understanding of the influence of estrogen exposure in human disease and the study of dehydroepiandrosterone in basic science and human disease.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.