ArticleEuropean journal of clinical pharmacology2010
Prescriptions as a proxy for asthma in children: a good choice?
Article in European journal of clinical pharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 22 citations in OpenAlex.
- Pertussis immunization in infancy and adolescent asthma medication.Pediatrics · 2014Trial
- Antiasthmatic prescriptions in children with and without congenital anomalies: a population-based study.BMJ open · 2023Article
- Article
- Asthma prevalence and risk factors among children and adolescents living around an industrial area: a cross-sectional study.BMC public health · 2013Article
- Article
- Use of prescription paracetamol during pregnancy and risk of asthma in children: a population-based Danish cohort study.Clinical epidemiology · 2012Article
- Anti-asthma medication prescribing to children in the Lombardy Region of Italy: chronic versus new users.BMC pulmonary medicine · 2011Article
- Asthma diagnosis vs. analysis of anti-asthmatic prescriptions to identify asthma in children.European journal of clinical pharmacology · 2011Article
- Respiratory and mental health effects of wildfires: an ecological study in Galician municipalities (north-west Spain).Environmental health : a global access science source · 2011Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeStock et al. (Eur Respir J 25:47-53, 2005) recently estimated asthma prevalence in Germany using claims data on prescriptions and hospital diagnoses and found high prevalence peaks in infants. Our objective was to critically assess and discuss various aspects of identifying children with asthma using prescription data.
methodsWe replicated the selection procedure of Stock et al. using data on 290,919 children aged 0-17 years insured in the Gmünder ErsatzKasse (GEK) in 2005. Asthma prevalence was also estimated in a sample of 17,641 children aged 0-17 years participating in the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) from 2003 to 2006.
resultsIn children aged 0-4 years insured in the GEK, prevalences were found to range from 11.7 to 17.7% for boys and from 7.2 to 11.1% for girls when the criteria of Stock et al. were applied. A steady decline in prevalences was observed in older age groups. Asthma prevalence estimated in the KiGGS data showed a quite different distribution. In the age group 0-4 years, prevalences were found to range from 0 to 2.6% in boys and from 0 to 1.0% in girls; in children >4 years, prevalences were found to increase with increasing age.
conclusionsWhen additional validation studies were taken into account, asthma medications were found to be prescribed not only for asthma but also for other respiratory diseases. In addition, not all children with current asthma had prescriptions. We therefore conclude that asthma medications are therefore not a good proxy for the disease.
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