Trial reportCanadian respiratory journal
Admissions to Canadian hospitals for acute asthma: a prospective, multicentre study.
Trial report in Canadian respiratory journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 5 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Combined inhaled beta-agonist and anticholinergic agents for emergency management in adults with asthma.The Cochrane database of systematic reviews · 2017Pooled it
- Clinical, economic, and humanistic burden of asthma in Canada: a systematic review.BMC pulmonary medicine · 2013Pooled it
- Inhaled steroids for acute asthma following emergency department discharge.The Cochrane database of systematic reviews · 2012Pooled it
- Intravenous beta(2)-agonists versus intravenous aminophylline for acute asthma.The Cochrane database of systematic reviews · 2012Pooled it
- Early use of inhaled corticosteroids in the emergency department treatment of acute asthma.The Cochrane database of systematic reviews · 2012Pooled it
- The Risk-Benefit Balance of Oral Corticosteroid Treatment for Asthma Attacks: A Discrete Choice Experiment of Patients and Healthcare Professionals in the UK and New Zealand.Respirology (Carlton, Vic.) · 2025Article
- Forecasting Hospitalization for Adult Asthma Patients in Emergency Departments Based on Multiple Environmental and Clinical Factors.Journal of asthma and allergy · 2025Article
- Effective Asthma Management: Is It Time to Let the AIR out of SABA?Journal of clinical medicine · 2020Review
- Management of severe asthma exacerbation: guidelines from the Société Française de Médecine d'Urgence, the Société de Réanimation de Langue Française and the French Group for Pediatric Intensive Care and Emergencies.Annals of intensive care · 2019Review
- Engaging patients and primary care providers in the design of novel opinion leader based interventions for acute asthma in the emergency department: a mixed methods study.BMC health services research · 2018Article
- Increased health service use for asthma, but decreased for COPD: Northumbrian hospital episodes, 2013-2014.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016Article
- Asthma length of stay in hospitals in London 2001-2006: demographic, diagnostic and temporal factors.PloS one · 2011Article
- Outcomes following chronic obstructive pulmonary disease presentations to emergency departments in Alberta: a population-based study.Canadian respiratory journalArticle
- Asthma in the emergency room in Canada.Canadian respiratory journalArticle
- GEMA 5.3. Spanish Guideline on the Management of Asthma.Open respiratory archivesArticle
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAsthma exacerbations constitute one of the most common causes of emergency department (ED) attendance in most developed countries. While severe asthma often requires hospitalization, variability in admission practices has been observed.
objectiveTo describe the factors associated with admission to Canadian hospitals for acute asthma after ED treatment.
methodsSubjects 18 to 55 years of age treated for acute asthma in 20 Canadian EDs prospectively underwent a structured ED interview (n=695) and telephone interview two weeks later.
resultsThe median age of the patients was 30 years, and the majority were women (62.8%). The admission rate was 13.1% (95% CI 10.7% to 15.8%). Admitted patients were older, more often receiving oral or inhaled corticosteroids at presentation, and more frequently receiving systemic corticosteroids and magnesium sulphate in the ED. Similar proportions received beta-2 agonists and/or ipratropium bromide within 1 h of arrival. On multivariable analyses, factors associated with admission included age, previous admission in the past two years, more than eight beta-2 agonist puffs in the past 24 h, a Canadian Triage and Acuity Score of 1 to 2, a respiratory rate of greater than 22 breaths/min and an oxygen saturation of less than 95%.
conclusionThe admission rate for acute asthma from these Canadian EDs was lower than reported in other North American studies. The present study provides insight into practical factors associated with admission for acute asthma and highlights the importance of history and asthma severity markers on ED decision making. Further efforts to standardize ED management and expedite admission decision-making appear warranted.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.