GuidelineCanadian respiratory journal
Canadian Thoracic Society Asthma Management Continuum--2010 Consensus Summary for children six years of age and over, and adults.
Guideline in Canadian respiratory journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 11 syntheses or guidelines pooled it, 203 citations in OpenAlex.
- Management of asthma exacerbations in the paediatric population: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2021Pooled it
- School-based self-management interventions for asthma among primary school children: a systematic review.NPJ primary care respiratory medicine · 2021Pooled it
- Addition of anti-leukotriene agents to inhaled corticosteroids for adults and adolescents with persistent asthma.The Cochrane database of systematic reviews · 2017Pooled it
- A systematic review of adverse drug events associated with administration of common asthma medications in children.PloS one · 2017Pooled it
- Addition of long-acting beta2-agonists to inhaled corticosteroids for chronic asthma in children.The Cochrane database of systematic reviews · 2015Pooled it
- Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma.The Cochrane database of systematic reviews · 2014Pooled it
- Addition of anti-leukotriene agents to inhaled corticosteroids in children with persistent asthma.The Cochrane database of systematic reviews · 2013Pooled it
- Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children.The Cochrane database of systematic reviews · 2012Pooled it
- Canadian Thoracic Society 2012 guideline update: Diagnosis and management of asthma in preschoolers, children and adults: executive summary.Canadian respiratory journalGuideline
- Canadian Thoracic Society 2012 guideline update: diagnosis and management of asthma in preschoolers, children and adults.Canadian respiratory journalGuideline
- Alpha-1 antitrypsin deficiency targeted testing and augmentation therapy: a Canadian Thoracic Society clinical practice guideline.Canadian respiratory journalGuideline
- Impact of Adding a Decision Aid to Patient Education in Adults with Asthma: A Randomized Clinical Trial.PloS one · 2017Trial
- Do Patients of Subspecialist Physicians Benefit from Written Asthma Action Plans?American journal of respiratory and critical care medicine · 2015Trial
- Asthma and chronic obstructive pulmonary disease guideline implementation: lessons learned on recruitment of primary care physicians to a knowledge translation study.Canadian respiratory journalTrial
- Effects of a short course of inhaled corticosteroids in noneosinophilic asthmatic subjects.Canadian respiratory journalTrial
- Comparative predictive modeling of pediatric spirometry reference equations in Jordanian children: Complex versus simple models.PLOS digital health · 2026Article
- Evidence-Based Clinical Recommendations for the Appropriate Use of Diagnostic Tests in Pediatric Allergology: Focus on Asthma, Rhinoconjunctivitis, and Keratoconjunctivitis Vernal.Journal of clinical medicine · 2026Review
- The clinical value and most informative threshold of polygenic risk score in the Quebec City Case-Control Asthma Cohort.BMC pulmonary medicine · 2025Article
- Impact of COVID-19 on asthma control in Kirkuk City: an analysis of post-pandemic trends.Journal of medicine and life · 2024Article
- Factors influencing poor response to type 2 targeted therapies in severe asthma: a retrospective cohort study.BMC pulmonary medicine · 2023Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 10 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectiveTo integrate new evidence into the Canadian Asthma Management Continuum diagram, encompassing both pediatric and adult asthma.
methodsThe Canadian Thoracic Society Asthma Committee members, comprised of experts in pediatric and adult respirology, allergy and immunology, emergency medicine, general pediatrics, family medicine, pharmacoepidemiology and evidence-based medicine, updated the continuum diagram, based primarily on the 2008 Global Initiative for Asthma guidelines, and performed a focused review of literature pertaining to key aspects of asthma diagnosis and management in children six years of age and over, and adults.
resultsIn patients six years of age and over, management of asthma begins with establishing an accurate diagnosis, typically by supplementing medical history with objective measures of lung function. All patients and caregivers should receive self-management education, including a written action plan. Inhaled corticosteroids (ICS) remain the first-line controller therapy for all ages. When asthma is not controlled with a low dose of ICS, the literature supports the addition of long-acting beta2-agonists in adults, while the preferred approach in children is to increase the dose of ICS. Leukotriene receptor antagonists are acceptable as second-line monotherapy and as an alternative add-on therapy in both age groups. Antiimmunoglobulin E therapy may be of benefit in adults, and in children 12 years of age and over with difficult to control allergic asthma, despite high-dose ICS and at least one other controller.
conclusionsThe foundation of asthma management is establishing an accurate diagnosis based on objective measures (eg, spirometry) in individuals six years of age and over. Emphasis is placed on the similarities and differences between pediatric and adult asthma management approaches to achieve asthma control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.