Evidence map›Paper›PMID 20186330›Full record

ArticlePLoS neglected tropical diseases2010

The feasibility of canine rabies elimination in Africa: dispelling doubts with data.

Tiziana Lembo, Katie Hampson, Magai T Kaare, Eblate Ernest, Darryn Knobel, Rudovick R Kazwala, Daniel T Haydon, Sarah Cleaveland

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 216 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
216citing papers in PubMed, 2 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

216 citing papers in PubMed, 2 syntheses or guidelines pooled it, 401 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  12. Rabies post-exposure prophylaxis in India: a SWOT analysis.Therapeutic advances in vaccines and immunotherapy · 2026
    Review
  13. Article
  14. Article
  15. Article
  16. Human rabies exposure and associated risk factors in North-West Ethiopia.Public health in practice (Oxford, England) · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Rabies elimination in the WHO African Region.Bulletin of the World Health Organization · 2025
    Article

156 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Tiziana LemboBoyd Orr Centre for Population and Ecosystem Health, University of Glasgow, Glasgow, United Kingdom. T.Lembo@vet.gla.ac.uk
Katie Hampson
Magai T Kaare
Eblate Ernest
Darryn Knobel
Rudovick R Kazwala
Daniel T Haydon
Sarah Cleaveland
Glasgow Centre for Population Health · GBTanzania Wildlife Research Institute · TZSokoine University of Agriculture · TZUniversity of Glasgow · GBUniversity of Sheffield · GB

Funding

PHS HHS DEB0225453Wellcome Trust 082715
6 · The paper itself

Abstract

backgroundCanine rabies causes many thousands of human deaths every year in Africa, and continues to increase throughout much of the continent. METHODOLOGY/PRINCIPAL

findingsThis paper identifies four common reasons given for the lack of effective canine rabies control in Africa: (a) a low priority given for disease control as a result of lack of awareness of the rabies burden; (b) epidemiological constraints such as uncertainties about the required levels of vaccination coverage and the possibility of sustained cycles of infection in wildlife; (c) operational constraints including accessibility of dogs for vaccination and insufficient knowledge of dog population sizes for planning of vaccination campaigns; and (d) limited resources for implementation of rabies surveillance and control. We address each of these issues in turn, presenting data from field studies and modelling approaches used in Tanzania, including burden of disease evaluations, detailed epidemiological studies, operational data from vaccination campaigns in different demographic and ecological settings, and economic analyses of the cost-effectiveness of dog vaccination for human rabies prevention. CONCLUSIONS/SIGNIFICANCE: We conclude that there are no insurmountable problems to canine rabies control in most of Africa; that elimination of canine rabies is epidemiologically and practically feasible through mass vaccination of domestic dogs; and that domestic dog vaccination provides a cost-effective approach to the prevention and elimination of human rabies deaths.

Indexed as

AfricaAnimalsCommunicable Disease ControlDog DiseasesDogsHumansMass VaccinationRabiesRabies VaccinesVaccinationRabies Vaccines

Identifiers

PMID20186330
PMCPMC2826407
OpenAlexW2065928396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.