ArticleClinics (Sao Paulo, Brazil)2010
Evaluation of serum paraoxonase and arylesterase activities in ankylosing spondylitis patients.
Article in Clinics (Sao Paulo, Brazil), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 32 citations in OpenAlex.
- Association of paraoxonase 1 activity and insulin resistance models in type 2 diabetes mellitus: Cross-sectional study.Journal of the Chinese Medical Association : JCMA · 2022Article
- Article
- Decreases in Paraoxonase-1 Activities Promote a Pro-inflammatory Effect of Lipids Peroxidation Products in Non-smoking and Smoking Patients with Acute Pancreatitis.International journal of medical sciences · 2018Article
- Correlation of Paraoxonase Status with Disease Activity Score and Systemic Inflammation in Rheumatoid Arthritic Patients.Journal of clinical and diagnostic research : JCDR · 2016Article
- Serum paraoxonase and arylesterase activities in patients with chronic otitis media.Redox report : communications in free radical research · 2015Article
- Evaluation of paraoxonase and arylesterase activities in Egyptian patients with ankylosing spondylitis.Rheumatology international · 2013Article
- Vitamin D status in patients with Behcet's Disease.Clinics (Sao Paulo, Brazil) · 2011Article
- Aqueous humor heat-shock protein 70, periostin, and irisin levels in patients with pseudoexfoliation syndrome.Arquivos brasileiros de oftalmologiaArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to investigate the activities of serum paraoxonase and arylesterase in patients with ankylosing spondylitis with respect to those of healthy controls, to assess whether these enzyme levels are related to disease activity and functional capacity.
methodsThe study included 32 patients with ankylosing spondylitis whose diagnoses were made according to the modified New York criteria as well as 25 healthy controls matched for age and sex. The Bath Ankylosing Spondylitis Disease Activity Index and the Bath Ankylosing Spondylitis Functional Index were applied to the ankylosing spondylitis patients. As laboratory parameters, the erythrocyte sedimentation rate and serum C-reactive protein level were measured in patients and control subjects. Paraoxonase and arylesterase enzyme activities were measured using appropriate methods.
resultsNo statistically significant differences (p>0.05) were found between the ankylosing spondylitis patients and controls in terms of serum paraoxonase or arylesterase levels. Furthermore, there was no correlation between clinical and laboratory parameters in patients with ankylosing spondylitis.
conclusionSerum paraoxonase and arylesterase levels in ankylosing spondylitis patients may not differ from those of healthy controls, and there is no significant correlation between antioxidant parameters and the Bath Ankylosing Spondylitis Disease Activity Index or Bath Ankylosing Spondylitis Functional Index scores in ankylosing spondylitis patients. Further research is needed to provide deeper understanding of this disease.
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