Evidence map›Paper›PMID 20182700›Full record

ReviewDer Orthopade2010

[Cell therapy in bone-healing disorders].

M Jäger, P Hernigou, C Zilkens, M Herten, J Fischer, R Krauspe

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Orthopade, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Review
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  4. Article
  5. Article
  6. Article
  7. Arthroscopically assisted retrograde drilling of the humeral head with a guiding device.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2015
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

M JägerOrthopädische Klinik, Universitätsklinikum, Heinrich-Heine-Universität Düsseldorf, Moorenstrasse 5, 40225, Düsseldorf, Deutschland. Jaeger@med.uni-duesseldorf.de
P Hernigou
C Zilkens
M Herten
J Fischer
R Krauspe
Düsseldorf University Hospital · DECentre Hospitalier Universitaire Henri-Mondor · FRHeinrich Heine University Düsseldorf · DEOrthopädische Universitätsklinik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In addition to stabilizing osteosynthesis and autologous bone transplantation, so-called orthobiologics are playing an increasing role in the treatment of bone-healing disorders. Besides the application of different growth factors, new data in the literature suggest that cell therapeutic agents promote local bone regeneration. Due to ethical and biological considerations, clinical application of progenitor cells for the musculoskeletal system is limited to autologous postpartum stem cells. Here in particular, cell therapy with autologous progenitor cells in one surgical session has delivered first promising results. Based on a review of the literature and on our own experience with 75 patients, this article reviews the rationale and characteristics of the clinical application of cell therapy for the treatment of bony substance defects. Most clinical trials report successful bone regeneration after the application of mixed cell populations from bone marrow.

Indexed as

AdolescentBone CystsBone NeoplasmsBone RegenerationBone TransplantationCell DifferentiationChildChondromaCombined Modality TherapyDurapatiteFracture HealingHumansMesenchymal Stem Cell TransplantationOsteoblastsTissue and Organ HarvestingDurapatite

Identifiers

PMID20182700
OpenAlexW3602748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.