Evidence map›Paper›PMID 20182541›Full record

ReviewJournal of biomedicine & biotechnology2010

Tight junctions in salivary epithelium.

Olga J Baker

Abstract readReview
In one paragraph

Review in Journal of biomedicine & biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Article
  3. Salivary Gland Bioengineering.Bioengineering (Basel, Switzerland) · 2023
    Review
  4. Review
  5. Xerostomia and Its Cellular Targets.International journal of molecular sciences · 2023
    Review
  6. Bioengineering in salivary gland regeneration.Journal of biomedical science · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Immunobiology of T Cells in Sjögren's Syndrome.Clinical reviews in allergy & immunology · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Cell junctions and oral health.EXCLI journal · 2019
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Olga J BakerDepartment of Oral Biology, University at Buffalo, State University of New York, Buffalo, NY 14214-30932, USA. olgabake@buffalo.edu

Funding

P2Y2R MEDIATED IMMUNE RESPONSES IN SALIVARY GLAND DYSFUNCTIONK08DE017633 · NIDCR · UNIVERSITY OF MISSOURI-COLUMBIA · PI BAKER, OLGA JULIANA · 2006 to 2008
$267k
NIDCR NIH HHS K08 DE017633NIDCR NIH HHS K08 DE017633-01
6 · The paper itself

Abstract

Epithelial cell tight junctions (TJs) consist of a narrow belt-like structure in the apical region of the lateral plasma membrane that circumferentially binds each cell to its neighbor. TJs are found in tissues that are involved in polarized secretions, absorption functions, and maintaining barriers between blood and interstitial fluids. The morphology, permeability, and ion selectivity of TJ vary among different types of tissues and species. TJs are very dynamic structures that assemble, grow, reorganize, and disassemble during physiological or pathological events. Several studies have indicated the active role of TJ in intestinal, renal, and airway epithelial function; however, the functional significance of TJ in salivary gland epithelium is poorly understood. Interactions between different combinations of the TJ family (each with their own unique regulatory proteins) define tissue specificity and functions during physiopathological processes; however, these interaction patterns have not been studied in salivary glands. The purpose of this review is to analyze some of the current data regarding the regulatory components of the TJ that could potentially affect cellular functions of the salivary epithelium.

Indexed as

AnimalsCell Adhesion MoleculesCell LineCell Line, TumorCell MembraneClaudinsDogsEpithelial CellsHumansMembrane ProteinsModels, BiologicalOccludinRatsSalivary GlandsTight JunctionsCell Adhesion MoleculesClaudinsMembrane ProteinsOccludinOCLN protein, humanOcln protein, rat

Identifiers

PMID20182541
PMCPMC2825559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.