Evidence map›Paper›PMID 20182528›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2009

Do the Symptom-Based, Rome Criteria of Irritable Bowel Syndrome Lead to Better Diagnosis and Treatment Outcomes? The Con Argument.

Michael Camilleri

Open access · greenAbstract read
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Sex as a biological variable in irritable bowel syndrome.Neurogastroenterology and motility · 2020
    Review
  2. Article
  3. Article
  4. Article
  5. Is irritable bowel syndrome an organic disorder?World journal of gastroenterology · 2014
    Review
  6. Advances in understanding of bile acid diarrhea.Expert review of gastroenterology & hepatology · 2014
    Review
  7. Managing irritable bowel syndrome.The American journal of nursing · 2013
    Review
  8. Irritable bowel syndrome: how useful is the term and the 'diagnosis'?Therapeutic advances in gastroenterology · 2012
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Michael CamilleriClinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), College of Medicine, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic · US

Funding

ALPHA 2 ADRENERGIC CONTROL OF COLONIC FUNCTION IN IBSR01DK054681 · NIDDK · MAYO CLINIC ROCHESTER · PI CAMILLERI, MICHAEL L · 1999 to 2007
$1.5M
Irritable bowel syndrome-diarrhea: the role of gluten intolerance and HLA-DQ2RC1DK086182 · NIDDK · MAYO CLINIC ROCHESTER · PI CAMILLERI, MICHAEL L. · 2009 to 2010
$1.0M
Cannabinoid Mechanisms in Human Gastrointestinal Motor and Sensory FunctionsR01DK079866 · NIDDK · MAYO CLINIC ROCHESTER · PI CAMILLERI, MICHAEL L. · 2009 to 2010
$752k
NIDDK NIH HHS R01 DK054681NIDDK NIH HHS R01 DK079866NIDDK NIH HHS RC1 DK086182
6 · The paper itself

Abstract

Some claim that symptom-based Rome criteria are diagnostic and enhance clinical practice and choice of therapy for patients presenting with gastrointestinal symptoms. This overview focuses on lower gastrointestinal symptoms: constipation, diarrhea, pain and bloating. The main con arguments for using such criteria for diagnosis are: insufficient specificity, overlap of symptom-based categories or disorders, insufficient and therefore non-specific characterization of pain in the criteria, inability to differentiate the "mimics" of IBS-C and IBS-D, and inability to optimize treatment for IBS-M or bloating in the absence of objective measurements. While doctors may not land in trouble using "symptom diagnosis" of IBS, this should not deter them from optimizing diagnosis and treatment of diseases associated with gastrointestinal dysfunction.

Identifiers

PMID20182528
PMCPMC2822078
OpenAlexW1965945782

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.