Evidence map›Paper›PMID 20182118›Full record

ArticleAcademic medicine : journal of the Association of American Medical Colleges2010

Linking scientific discovery and better health for the nation: the first three years of the NIH's Clinical and Translational Science Awards.

Robert M Califf, Lars Berglund, Principal Investigators of National Institutes of Health Clinical and Translational Science Awards

Abstract read
In one paragraph

Article in Academic medicine : journal of the Association of American Medical Colleges, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Review
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  15. Conflicts of Interest and Distribution of Resources to Community Partners: An Organizational Ethics Dilemma.Progress in community health partnerships : research, education, and action · 2017
    Article
  16. Beyond bench and bedside: disentangling the concept of translational research.Health care analysis : HCA : journal of health philosophy and policy · 2015
    Article
  17. Model for a university-based clinical research development infrastructure.Academic medicine : journal of the Association of American Medical Colleges · 2015
    Article
  18. Article
  19. Doctoral programs to train future leaders in clinical and translational science.Academic medicine : journal of the Association of American Medical Colleges · 2013
    Article
  20. Restructuring academic health centers to advance interdisciplinary collaborations: opportunities for psychiatry departments.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Robert M CaliffDuke Translational Medicine Institute, Durham, North Carolina 27710, USA. robert.califf@duke.edu
Lars Berglund
Principal Investigators of National Institutes of Health Clinical and Translational Science Awards

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
UC DAVIS CLINICAL AND TRANSLATIONAL SCIENCE CENTER: BPCAUL1RR024146 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2006 to 2011
$27.0M
NCRR NIH HHS 1UL1 RR024153-01NCRR NIH HHS UL1 RR024146NCRR NIH HHS UL1 RR024153
6 · The paper itself

Abstract

A comprehensive system for translating basic biomedical research into useful and effectively implemented clinical diagnostic, preventive, and therapeutic practices is essential to the nation's health. The state of clinical and translational research (CTR) in the United States, however, has been characterized as fragmented, slow, expensive, and poorly coordinated. As part of its Roadmap Initiative, the National Institutes of Health instituted the Clinical and Translational Science Awards (CTSA), a sweeping and ambitious program designed to transform the conduct of biomedical research in the United States by speeding the translation of scientific discoveries into useful therapies and then developing methods to ensure that those therapies reach the patients who need them the most. The authors review the circumstances of the U.S. biomedical research enterprise that led to the creation of the CTSA and discuss the initial strategic plan of the CTSA, which was developed from the first three years of experience with the program and was designed to overcome organizational, methodological, and cultural barriers within and among research institutions. The authors also describe the challenges encountered during these efforts and discuss the promise of this vital national health care initiative, which is essential to creating a pipeline for the scientific workforce needed to conduct research that will, in turn, provide a rational evidence base for better health in the United States.

Indexed as

Awards and PrizesNational Institutes of Health (U.S.)Translational Research, BiomedicalHealthTime FactorsUnited States

Identifiers

PMID20182118
PMCPMC4552187

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.