Evidence map›Paper›PMID 20181779›Full record

ArticleStatistical methods in medical research2010

Bayesian credible intervals for binomial proportions in a single patient trial.

Jacob J Oleson

Open access · greenAbstract read
In one paragraph

Article in Statistical methods in medical research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 19 citations in OpenAlex.

  1. Continuity corrected Wilson interval for the difference of two independent proportions.Journal of statistical theory and applications : JSTA · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jacob J OlesonDepartment of Biostatistics, The University of Iowa, 200 Hawkins Drive, The University of Iowa, Iowa City, IA 52242-1009, USA. jacob-oleson@uiowa.edu
University of Iowa · US

Funding

Speech Production &LanguageP50DC000242 · NIDCD · UNIVERSITY OF IOWA · PI Bruce Jay Gantz · 1989 to 2026
$58.8M
NIDCD NIH HHS 5 P50 DC00242NIDCD NIH HHS P50 DC000242
6 · The paper itself

Abstract

Practitioners are often asking if the treatment successfully improved performance. Many times this question is directed towards the outcome of a single individual. In this article, we develop a method to assess the improvement of a single individual who is administered a test of percent correct at pre-treatment and post-treatment. A Bayesian approach is taken where the number correct is modelled as a binomial random variable and the percent correct is set to a beta prior distribution. The first model assumes percent correct at pre-test is equal to the percent correct at post-test and the posterior predictive distribution is used to evaluate the change in the number correct. We subsequently model the proportions correct at pre-test and post-test as unequal. The second model then assumes independent proportions and the third assumes correlated beta distributions for the two proportions. 95% credible intervals are calculated for the various methods for number of correct at post-test given a particular level at pre-test. An example using data from a cochlear implant clinical trial is presented where clinicians recorded percent correct in a consonant-nucleus-consonant test.

Indexed as

Bayes TheoremBinomial DistributionBiostatisticsClinical Trials as TopicCochlear ImplantsHumansModels, StatisticalTreatment Outcome

Identifiers

PMID20181779
PMCPMC3307549
OpenAlexW2148746498

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.