ArticleJournal of virology2010
Structural insights into the molecular mechanisms of cauliflower mosaic virus transmission by its insect vector.
Article in Journal of virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Law and Order of Colloidal Tectonics: From Molecules to Self-Assembled Colloids.Molecules (Basel, Switzerland) · 2024Review
- Aphids on Aphid-Susceptible Cultivars Have Easy Access to Turnip Mosaic Virus, and Effective Inoculation on Aphid-Resistant Cultivars of Oilseed Rape (Plants (Basel, Switzerland) · 2023Article
- Turnip Mosaic Virus Infection Differentially Modifies Cabbage Aphid Probing Behavior in Spring and Winter Oilseed Rape (Insects · 2022Article
- Molecular dynamics investigations for the prediction of molecular interaction of cauliflower mosaic virus transmission helper component protein complex withVirusdisease · 2019Article
- Pharmacological analysis of transmission activation of two aphid-vectored plant viruses, turnip mosaic virus and cauliflower mosaic virus.Scientific reports · 2019Article
- Tenuivirus utilizes its glycoprotein as a helper component to overcome insect midgut barriers for its circulative and propagative transmission.PLoS pathogens · 2019Article
- Setting Up Shop: The Formation and Function of the Viral Factories ofFrontiers in plant science · 2017Review
- Plant Virus-Insect Vector Interactions: Current and Potential Future Research Directions.Viruses · 2016Review
- Imperfection works: Survival, transmission and persistence in the system of Heliothis virescens ascovirus 3h (HvAV-3h), Microplitis similis and Spodoptera exigua.Scientific reports · 2016Article
- Comparative analysis of endogenous plant pararetroviruses in cultivated and wild Dahlia spp.Virus genes · 2014Article
- Virus factories of cauliflower mosaic virus are virion reservoirs that engage actively in vector transmission.Journal of virology · 2013Article
- A virus responds instantly to the presence of the vector on the host and forms transmission morphs.eLife · 2013Article
- Host cell processes to accomplish mechanical and non-circulative virus transmission.Protoplasma · 2012Review
- Top 10 plant viruses in molecular plant pathology.Molecular plant pathology · 2011Review
- Structural insights into viral determinants of nematode mediated Grapevine fanleaf virus transmission.PLoS pathogens · 2011Article
- VAPA, an innovative "virus-acquisition phenotyping assay" opens new horizons in research into the vector-transmission of plant viruses.PloS one · 2011Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cauliflower mosaic virus (CaMV) is transmitted from plant to plant through a seemingly simple interaction with insect vectors. This process involves an aphid receptor and two viral proteins, P2 and P3. P2 binds to both the aphid receptor and P3, itself tightly associated with the virus particle, with the ensemble forming a transmissible viral complex. Here, we describe the conformations of both unliganded CaMV P3 protein and its virion-associated form. X-ray crystallography revealed that the N-terminal domain of unliganded P3 is a tetrameric parallel coiled coil with a unique organization showing two successive four-stranded subdomains with opposite supercoiling handedness stabilized by a ring of interchain disulfide bridges. A structural model of virus-liganded P3 proteins, folding as an antiparallel coiled-coil network coating the virus surface, was derived from molecular modeling. Our results highlight the structural and biological versatility of this coiled-coil structure and provide new insights into the molecular mechanisms involved in CaMV acquisition and transmission by the insect vector.
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