ArticleJournal of the American Society for Mass Spectrometry2010
Comparison of the internal energy deposition of direct analysis in real time and electrospray ionization time-of-flight mass spectrometry.
Article in Journal of the American Society for Mass Spectrometry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed.
- Species-specific optimization of oxylipin ionization in LC-MS: a design of experiments approach to improve sensitivity.Analytical and bioanalytical chemistry · 2025Article
- Ion Heating in Advanced Dielectric Barrier Discharge Ion Sources for Ambient Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2023Article
- Internal Energy Deposition in Infrared Matrix-Assisted Laser Desorption Electrospray Ionization With and Without the Use of Ice as a Matrix.Journal of the American Society for Mass Spectrometry · 2019Article
- The Ion Source of Nitrogen Direct Analysis in Real-Time Mass Spectrometry as a Highly Efficient Reactor: Generation of Reactive Oxygen Species.Journal of the American Society for Mass Spectrometry · 2019Article
- Sweep Jet Collection Laser-Induced Acoustic Desorption Atmospheric Pressure Photoionization for Lipid Analysis Applications.Journal of the American Society for Mass Spectrometry · 2019Article
- Recent advances in ambient mass spectrometry of trace explosives.The Analyst · 2018Review
- Aerosol Vacuum-Assisted Plasma Ionization (Aero-VaPI) Coupled to Ion Mobility-Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2018Article
- Collision Induced Dissociation of Benzylpyridinium-Substituted Porphyrins: Towards a Thermometer Scale for Multiply Charged Ions?Journal of the American Society for Mass Spectrometry · 2018Article
- Rapid detection ofForensic toxicology · 2018Article
- Comparison of Internal Energy Distributions of Ions Created by Electrospray Ionization and Laser Ablation-Liquid Vortex Capture/Electrospray Ionization.Journal of the American Society for Mass Spectrometry · 2015Article
- Internal energy deposition for low energy, femtosecond laser vaporization and nanospray post-ionization mass spectrometry using thermometer ions.Journal of the American Society for Mass Spectrometry · 2015Article
- Plasma-spray ionization (PLASI): a multimodal atmospheric pressure ion source for liquid stream analysis.Journal of the American Society for Mass Spectrometry · 2014Article
- Determination of internal energy distributions of laser electrospray mass spectrometry using thermometer ions and other biomolecules.Journal of the American Society for Mass Spectrometry · 2014Article
- Surface acoustic wave nebulization produces ions with lower internal energy than electrospray ionization.Journal of the American Society for Mass Spectrometry · 2012Article
- Biomarkers of whale shark health: a metabolomic approach.PloS one · 2012Article
- Sensitivity "hot spots" in the direct analysis in real time mass spectrometry of nerve agent simulants.Journal of the American Society for Mass Spectrometry · 2012Article
- Poor quality drugs: grand challenges in high throughput detection, countrywide sampling, and forensics in developing countries.The Analyst · 2011Article
- Thermometer Ions, Internal Energies, and In-Source Fragmentation in Ambient Ionization.Mass spectrometry reviewsReview
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The internal energy (E(int)) distributions of a series of p-substituted benzylpyridinium ions generated by both direct analysis in real time (DART) and electrospray ionization (ESI) were compared using the "survival yield" method. DART mean E(int) values at gas flow rates of 2, 4, and 6 L min(-1), and at set temperatures of 175, 250, and 325 degrees C were in the 1.92-2.21 eV range. ESI mean E(int) at identical temperatures in aqueous and 50% methanol solutions ranged between 1.71 and 1.96 eV, and 1.53 and 1.63 eV, respectively. Although the results indicated that ESI is a "softer" ionization technique than DART, there was overlap between the two techniques for the particular time-of-flight mass spectrometer used. As a whole, there was an increase in E(int) with increasing reactive and drying gas temperatures for DART and ESI, respectively, indicating thermal ion activation. Three dimensional computational fluid dynamic simulations in combination with direct temperature measurements within the DART ionization region revealed complex inversely coupled fluid-thermal phenomena affecting ion E(int) values during atmospheric transport. Primarily, that DART gas temperature in the ionization region was appreciably less than the set gas temperature of DART due to the set gas flow rates. There was no evidence of E(int) deposition pathways from metastable-stimulated desorption, but fragmentation induced by high-energy helium metastables was observed at the highest gas flow rates and temperatures.
Identifiers
20181493What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.