ArticleCough (London, England)2010
Perception of urge-to-cough and dyspnea in healthy smokers with decreased cough reflex sensitivity.
Article in Cough (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 33 citations in OpenAlex.
- Evidence for AlphaThe Journal of pharmacology and experimental therapeutics · 2022Article
- Impact of Tussigenic Stimuli on Perceived Upper Airway Sensation and Motor Cough Response Following Total Laryngectomy.Frontiers in physiology · 2020Article
- Computerised respiratory sounds can differentiate smokers and non-smokers.Journal of clinical monitoring and computing · 2017Article
- Effect of viral upper respiratory tract infection on cough reflex sensitivity.Journal of thoracic disease · 2014Review
- Gender differences in the effect of urge-to-cough and dyspnea on perception of pain in healthy adults.Physiological reports · 2014Article
- Inhibitory effect of cervical trachea and chest wall vibrations on cough reflex sensitivity and perception of urge-to-cough in healthy male never-smokers.Cough (London, England) · 2013Article
- Prospective description of coughing, hemodynamic changes, and oxygen desaturation during endoscopic sedation.Digestive diseases and sciences · 2012Article
- Aging deteriorated perception of urge-to-cough without changing cough reflex threshold to citric acid in female never-smokers.Cough (London, England) · 2011Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough cigarette smoking has been implicated as an important risk factor for the development of respiratory symptoms, the perceptional aspects of two symptoms in smokers have not been fully elucidated. Therefore, we simultaneously evaluated the cough reflex sensitivity, the cognition of urge-to-cough and perception of dyspnea in both healthy smokers and non-smokers.
methodsFourteen male healthy never-smokers and 14 age-matched male healthy current-smokers were recruited via public postings. The cough reflex sensitivity and the urge-to-cough were evaluated by the inhalation of citric acid. The perception of dyspnea was evaluated by Borg scores during applications of external inspiratory resistive loads.
resultsThe cough reflex threshold to citric acid, as expressed by the lowest concentration of citric acid that elicited two or more coughs (C2) and the lowest concentration of citric acid that elicited five or more coughs (C5) in smokers was significantly higher than in non-smokers. The urge-to-cough log-log slope in smokers was significantly milder than that of non-smokers. There were no significant differences in the urge-to-cough threshold between non-smokers and smokers. There were no significant differences in perceptions of dyspnea between non-smokers and smokers.
conclusionsThe study showed that decreased cough reflex sensitivity in healthy smokers was accompanied by a decreased cognition of urge-to-cough whereas it was not accompanied by the alternation of perception of dyspnea. Physicians should pay attention to the perceptual alterations of cough in smokers.
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Registered trials
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