ArticleJournal of pediatric orthopedics2010
Prevalence of vitamin D insufficiency in African American children with forearm fractures: a preliminary study.
Article in Journal of pediatric orthopedics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02805647 (Association Between Vitamin D Receptor Polymorphism and Serum Vitamin D Levels in Children With Low-Energy Fractures), which is not on this map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Association Between Vitamin D Receptor Polymorphism and Serum Vitamin D Levels in Children With Low-Energy Fractures
Who cites it
13 citing papers in PubMed, 48 citations in OpenAlex.
- Vitamin D and Forearm Fractures in Children Preliminary Findings: Risk Factors and Correlation between Low-Energy and High-Energy Fractures.Children (Basel, Switzerland) · 2022Article
- Traumatic fractures in China from 2012 to 2014: a National Survey of 512,187 individuals.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Article
- Vitamin D and Fracture Risk in Early Childhood: A Case-Control Study.American journal of epidemiology · 2017Article
- Prevalence of vitamin D insufficiency in children with forearm fractures.Journal of children's orthopaedics · 2017Article
- Serum 25-hydroxyvitamin D status among Saudi children with and without a history of fracture.Journal of endocrinological investigation · 2016Article
- Evaluating Bone Health in Egyptian Children with Forearm Fractures: A Case Control Study.International journal of pediatrics · 2016Article
- Low Vitamin D Levels in Children with Fractures: a Comparative Cohort Study.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2015Article
- Vitamin D and skeletal health in infancy and childhood.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014Review
- The association between fracture rates and neighborhood characteristics in Washington, DC, children.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2013Article
- Prevalence of vitamin D insufficiency in Swiss teenagers with appendicular fractures: a prospective study of 100 cases.Journal of children's orthopaedics · 2012Article
- Status of vitamin D in children with sickle cell disease living in Madrid, Spain.European journal of pediatrics · 2012Article
- Vitamin D deficiency in children living in Jeddah, Saudi Arabia.Indian journal of endocrinology and metabolism · 2012Article
- Epidemiology of bone fracture across the age span in blacks and whites.The Journal of trauma · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesForearm fractures account for a significant proportion of childhood injuries and seem to be increasing in incidence. Poor vitamin D status increases overall fracture risk in infants with rickets and adults with osteoporosis. Children with vitamin D insufficiency (serum 25-hydroxy vitamin D level <20 ng/mL) have decreased bone mineral density (BMD) compared with children having normal vitamin D status. The relationship between vitamin D status and childhood forearm fracture has not been investigated.
methodsThis prospective study enrolled African American children, aged 5 to 9 years, with a forearm fracture. Bone health evaluation included measurement of serum 25-hydroxy vitamin D level and BMD by dual energy x-ray absorptiometry scan. Univariable analyses were used to test the associations between fracture status and the independent variables, serum vitamin D level and BMD.
resultsVitamin D levels were available for 17 cases. The mean (+/-SD) 25-hydroxy vitamin D level was 20.1 (+/-7.3) ng/mL with a range of 10 to 38 ng/mL. The mean of this group was at the cut point for vitamin D insufficiency. Ten cases (59%) were vitamin D insufficient. Dual energy x-ray absorptiometry scan results for these patients were consistent with normal bony mineralization for age.
conclusionsA significant proportion of African American children with fractures in our study have vitamin D insufficiency. Analysis of serum 25-hydroxy vitamin D levels and BMD in additional cases and controls will determine the significance of these findings. CLINICAL RELEVANCE: Vitamin D insufficiency may play a previously unrecognized role in childhood fractures. Strong consideration should be given to routine vitamin D testing in African American children with forearm fractures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.