ReviewCurrent biology : CB2010
The evolution of human genetic and phenotypic variation in Africa.
Review in Current biology : CB, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neandertal demise: an archaeological analysis of the modern human superiority complex.PloS one · 2014Pooled it
- Precision oncology without borders: the role of biobanking in integrating Africa's genetic diversity into global genomic research.NPJ precision oncology · 2026Review
- Variation and selection at predicted G-quadruplexes across the human pangenome.bioRxiv : the preprint server for biology · 2026Article
- Epidemiological insights and genetic diversity of the Duffy binding protein of Plasmodium vivax in Duffy-negative Cameroonians.PLoS neglected tropical diseases · 2026Article
- S4-multi: Enhancing polygenic score prediction in ancestrally diverse populations.HGG advances · 2026Article
- The Diverse Genetic Landscape of Hearing Impairment in South African Families.Clinical genetics · 2025Article
- High resolution class I HLA-A, -B, and -C diversity in Eastern and Southern African populations.Scientific reports · 2025Article
- Deep learning insights into distinct patterns of polygenic adaptation across human populations.Nucleic acids research · 2024Article
- Dynamics of Myopia Progression in Ghana-Evidence From Clinical Practice: A Retrospective Cohort Study.Health science reports · 2024Article
- The African Human Microbiome Portal: a public web portal of curated metagenomic metadata.Database : the journal of biological databases and curation · 2024Article
- Hunter-gatherer genetics research: Importance and avenues.Evolutionary human sciences · 2024Article
- Article
- African genomes hold the key to accurate genetic risk prediction.Nature human behaviour · 2023Article
- Beta-cell dysfunction and insulin resistance in relation to abnormal glucose tolerance in African populations: can we afford to ignore the diversity within African populations?BMJ open diabetes research & care · 2022Article
- Role of Precision Oncology in Type II Endometrial and Prostate Cancers in the African Population: Global Cancer Genomics Disparities.International journal of molecular sciences · 2022Review
- African Genetic Representation in the Context of SARS-CoV-2 Infection and COVID-19 Severity.Frontiers in genetics · 2022Article
- High Genetic Diversity andFrontiers in cellular and infection microbiology · 2022Article
- Commodification of biomaterials and data when funding is contingent to transfer in biobank research.Medicine, health care, and philosophy · 2021Review
- Inferring archaic introgression from hominin genetic data.Evolutionary anthropology · 2021Review
- Human OMICs and Computational Biology Research in Africa: Current Challenges and Prospects.Omics : a journal of integrative biology · 2021Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Africa is the birthplace of modern humans, and is the source of the geographic expansion of ancestral populations into other regions of the world. Indigenous Africans are characterized by high levels of genetic diversity within and between populations. The pattern of genetic variation in these populations has been shaped by demographic events occurring over the last 200,000 years. The dramatic variation in climate, diet, and exposure to infectious disease across the continent has also resulted in novel genetic and phenotypic adaptations in extant Africans. This review summarizes some recent advances in our understanding of the demographic history and selective pressures that have influenced levels and patterns of diversity in African populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.