ArticleWiener klinische Wochenschrift2010
The association between body-mass index and patient outcome in septic shock: a retrospective cohort study.
Article in Wiener klinische Wochenschrift, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The obesity paradox in murine sepsis models: a systematic review and meta-analysis.Anaesthesiology intensive therapy · 2025Pooled it
- Frequency and mortality of septic shock in Europe and North America: a systematic review and meta-analysis.Critical care (London, England) · 2019Pooled it
- The role of increased body mass index in outcomes of sepsis: a systematic review and meta-analysis.BMC anesthesiology · 2017Pooled it
- Increased body mass index and adjusted mortality in ICU patients with sepsis or septic shock: a systematic review and meta-analysis.Critical care (London, England) · 2016Pooled it
- Do Obesity Classifications Create the Obesity Paradox? A Scoping Review of Obesity Definitions Applied in Sepsis Research.Clinical obesity · 2026Article
- Obesity promotes urinary tract infection by disrupting bladder focal adhesion kinase signaling.iScience · 2025Article
- Evaluating the obesity paradox in patients with sepsis and cancer.International journal of obesity (2005) · 2025Article
- The Association of Body Mass Index and Waist Circumference with Sepsis-Related Mortality in South Korea.Diagnostics (Basel, Switzerland) · 2024Article
- Role of obesity in lower mortality risk in sepsis: a meta-analysis of observational studies.American journal of translational research · 2024Review
- Association of obesity and mortality in sepsis patients: A meta-analysis from observational evidence.Heliyon · 2023Article
- Association of body mass index with mortality of sepsis or septic shock: an updated meta-analysis.Journal of intensive care · 2023Article
- Association between obesity and 1-year mortality in septic patients: a retrospective cohort study.BMJ open · 2023Article
- Associations of body mass index with severe outcomes of COVID-19 among critically ill elderly patients: A prospective study.Frontiers in nutrition · 2023Article
- Obesity and infectious diseases: pathophysiology and epidemiology of a double pandemic condition.International journal of obesity (2005) · 2022Review
- Impact of Body Mass Index on the Survival of Patients with Sepsis with Different Modified NUTRIC Scores.Nutrients · 2021Article
- Neutropenic enterocolitis-induced sepsis and disseminated intravascular coagulation after chemotherapy: a case report.BMC women's health · 2021Article
- The Association Between Body Mass Index and the Risk of Hospitalization and Mortality due to Infection: A Prospective Cohort Study.Open forum infectious diseases · 2021Article
- Review
- Does Obesity Protect Against Death in Sepsis? A Retrospective Cohort Study of 55,038 Adult Patients.Critical care medicine · 2019Article
- Impact of body mass index on survival of medical patients with sepsis: a prospective cohort study in a university hospital in China.BMJ open · 2018Article
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Authors and funding
9 authors.
Funding
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Abstract
backgroundIt is unknown whether body-mass index (BMI) and commonly defined BMI categories are associated with mortality in patients with septic shock.
methodsThe database of a multidisciplinary intensive care unit (ICU) was retrospectively screened for adult patients with septic shock. BMI, demographic, clinical and laboratory variables together with outcome measures were collected in all patients. Subjects were categorized as follows: underweight, BMI < 18.5; normal weight, BMI 18.5-24.9; overweight, BMI 25-29.9; obesity, BMI >or= 30. Bivariate and multivariate logistic regression models were used to evaluate the association between BMI and outcome parameters.
resultsIn total, 301 patients with septic shock were identified. BMI was bivariately associated with ICU mortality (OR 0.91; 95% CI 0.86-0.98; P = 0.007). There was no significant association between BMI and ICU mortality in the multivariate model but an increasing BMI tended to be associated with lower ICU mortality (OR 0.93; 95% CI 0.86-1.01; P = 0.09). Although overweight (OR 0.43; 95% CI 0.19-0.98; P = 0.04) and obese (OR 0.28; 95% CI 0.08-0.93; P = 0.04) patients had an independently lower risk of ICU death than those with normal weight, there was no difference in the risk of ICU death between normal weight and underweight patients (P = 0.22). A high BMI was independently associated with a lower frequency of acute delirium (P = 0.04) and a lower need for ICU re-admission (P = 0.001) but with a higher rate of ICU-acquired urinary tract infections (P = 0.02).
conclusionsBMI up to 50 does not appear to be associated with worse ICU and hospital mortality in patients with septic shock. In contrast, a high BMI may reduce the risk of death from septic shock.
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