Evidence map›Paper›PMID 20177772›Full record

ArticleChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2010

A unique late-replicating XY to autosome translocation in Peromyscus melanophrys.

Elisabeth E Mlynarski, Craig Obergfell, Michael J Dewey, Rachel J O'Neill

Abstract read
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In one paragraph

Article in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Peromyscus as a Mammalian epigenetic model.Genetics research international · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elisabeth E MlynarskiDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, 06269, USA.
Craig Obergfell
Michael J Dewey
Rachel J O'Neill

Funding

PEROMYSCUS SPERM: CRYOPRESERVATION &ARTIFICIAL INSEMINATIONP40RR014279 · NCRR · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FELDER, MICHAEL RAY, SZALAI, GABOR · 1999 to 2011
$2.5M
NCRR NIH HHS P40-RR14279
6 · The paper itself

Abstract

We report on the characterization of the Peromyscus melanophrys karyotype and sex chromosome system. Classic studies reported the sex chromosome system of this species may be as complex as an X(1)X(1)X(2)X(2)/X(1)X(2)Y(1)Y(2) and provided conflicting identification of the X chromosome. Using Peromyscus maniculatus chromosome paints, we have positively identified the sex chromosomes and clarified the sex determining system that once perplexed Peromyscus researchers. The sex chromosomes are characterized by a unique autosomal translocation of DNA shared between both the X and Y chromosomes. The translocated material is late replicating and heterochromatic yet retains the active chromatin conformation. Thus, autosomal regions derived from translocations involving repeat-rich material may retain some epigenetic marks specific to the sex chromosomes despite loss of epigenetic silencing activity.

Indexed as

Translocation, GeneticAnimalsChromosome PaintingDNA ReplicationFemaleHeterochromatinMalePeromyscusX ChromosomeX Chromosome InactivationY ChromosomeHeterochromatin

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.