ArticleJournal of experimental botany2010
Regulation of tissue-specific expression of SPATULA, a bHLH gene involved in carpel development, seedling germination, and lateral organ growth in Arabidopsis.
Article in Journal of experimental botany, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed, 104 citations in OpenAlex.
- Genome-Wide Identification and Characterization of bHLH Family inLife (Basel, Switzerland) · 2026Article
- Laminar patterning transcription factors orchestrate spatial metabolite partitioning in Capsicum fruit.Nature plants · 2026Article
- Identifying new players of gynoecium development using tissue-specific transcriptome data of Arabidopsis.Planta · 2025Article
- The Shock of Shatter: Understanding Silique and Silicle Dehiscence for Improving Oilseed Crops in Brassicaceae.Plant direct · 2025Review
- Genome-Wide Identification of theInternational journal of molecular sciences · 2025Article
- Evolution of the basic helix-loop-helix transcription factor SPATULA and its role in gynoecium development.Annals of botany · 2024Article
- A Model for the Gene Regulatory Network Along the Arabidopsis Fruit Medio-Lateral Axis: Rewiring the Pod Shatter Process.Plants (Basel, Switzerland) · 2024Article
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- Arabidopsis transcription factor TCP4 controls the identity of the apical gynoecium.The Plant cell · 2024Article
- EXPANSIN15 is involved in flower and fruit development in Arabidopsis.Plant reproduction · 2024Article
- Genome-wide identification of bHLH transcription factors and functional analysis in salt gland development of the recretohalophyte sea lavender (Horticulture research · 2024Article
- A Common Molecular Signature Indicates the Pre-Meristematic State of Plant Calli.International journal of molecular sciences · 2023Review
- Transcription FactorInternational journal of molecular sciences · 2023Article
- Novel Roles of SPATULA in the Control of Stomata and Trichome Number, and Anthocyanin Biosynthesis.Plants (Basel, Switzerland) · 2023Article
- Genetic and Phenotypic Analyses of Carpel Development in Arabidopsis.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Conserved hierarchical gene regulatory networks for drought and cold stress response inFrontiers in plant science · 2023Article
- Association mapping unravels the genetics controlling seedling drought stress tolerance in winter wheat.Frontiers in plant science · 2023Article
- Genome-wide analysis of basic helix-loop-helix (bHLH) transcription factors in Aquilaria sinensis.Scientific reports · 2022Article
- Gene expression analysis during the fruit development in dehiscent and indehiscentPhysiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- Gene regulation network analyses of pistil development in papaya.BMC genomics · 2022Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SPATULA is a bHLH transcription factor that promotes growth of tissues arising from the carpel margins, including the septum and transmitting tract. It is also involved in repressing germination of newly harvested seeds, and in inhibiting cotyledon, leaf, and petal expansion. Using a reporter gene construct, its expression profile was fully defined. Consistent with its known functions, SPT was expressed in developing carpel margin tissues, and in the hypocotyls and cotyledons of germinating seedlings, and in developing leaves and petals. It was also strongly expressed in tissues where no functions have been identified to date, including the dehiscence zone of fruits, developing anthers, embryos, and in the epidermal initials and new stele of root tips. The promoter region of SPT was dissected by truncation and deletion, and two main regions occupied by tissue-specific enhancers were identified. These were correlated with eight regions conserved between promoter regions of Arabidopsis, Brassica oleracea, and Brassica rapa. When transformed into Arabidopsis, the B. oleracea promoter drove expression in reproductive tissues mostly comparable to the equivalent Arabidopsis promoter. There is genetic evidence that SPT function in the gynoecium is associated with the perception of auxin. However, site-directed mutagenesis of three putative auxin-response elements had no detectable effect on SPT expression patterns. Even so, disruption of a putative E-box variant adjacent to one of these resulted in a loss of valve dehiscence zone expression. This expression was also specifically lost in mutants of another bHLH gene INDEHISCENT, indicating that IND may directly regulate SPT expression through this variant E-box.
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