Evidence map›Paper›PMID 20175863›Full record

ReviewJournal of internal medicine2010

The genetics of ischaemic stroke.

M Matarin, A Singleton, J Hardy, J Meschia

Abstract readReview
In one paragraph

Review in Journal of internal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Genetics of ischemic stroke in young adults.Circulation. Cardiovascular genetics · 2014
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Association of ALOX5AP with ischemic stroke in eastern Chinese.World journal of emergency medicine · 2012
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Genetics studies in ischaemic stroke.Translational stroke research · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

M MatarinLaboratory of Neurogenetics, NIA/NIH, Bethesda, MD, USA.
A Singleton
J Hardy
J Meschia

Funding

Genetic analysis in families with neurological diseaseZIAAG000958 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW · 2009 to 2024
$10.9M
Whole Genome Screen in families with Parkinson's diseaseZ01AG000958 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW B · 2003 to 2008
$1.4M
Genetics Of StrokeZIAAG000954 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW · 2009 to 2011
$815k
Intramural NIH HHS Z01 AG000958Medical Research Council G0701075NIA NIH HHS Z01 AG000958-06
6 · The paper itself

Abstract

In this review, we discuss the genetic factors in both the aetiology and treatment of ischaemic stroke. We discuss candidate gene association studies, family linkage studies and the more recent whole genome association studies and whole genome expression studies. We also briefly discuss genetic testing for stroke risk and genetic analysis of treatment complications.

Indexed as

Brain IschemiaGenetic LinkageGenetic Predisposition to DiseaseHumansPolymorphism, Single NucleotideRisk FactorsStroke

Identifiers

PMID20175863
PMCPMC4003485

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.