Evidence map›Paper›PMID 20175501›Full record

ArticleMedical physics2010

Dynamic multiple thresholding breast boundary detection algorithm for mammograms.

Yi-Ta Wu, Chuan Zhou, Heang-Ping Chan, Chintana Paramagul, Lubomir M Hadjiiski, Caroline Plowden Daly, Julie A Douglas, Yiheng Zhang, Berkman Sahiner, Jiazheng Shi and 1 more

Abstract readEvaluation Study
In one paragraph

Article in Medical physics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Yi-Ta WuDepartment of Radiology, University of Michigan, Ann Arbor Michigan 48109, USA. yitawu@itri.org.tw
Chuan Zhou
Heang-Ping Chan
Chintana Paramagul
Lubomir M Hadjiiski
Caroline Plowden Daly
Julie A Douglas
Yiheng Zhang
Berkman Sahiner
Jiazheng Shi
Jun Wei

Funding

Mapping Genes for Mammographic Breast DensityR01CA122844 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DOUGLAS, JULIE A. · 2007 to 2011
$3.0M
Digital Mammography: Advanced Computer-Aided Breast Can*R01CA095153 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHAN, HEANG-PING · 2003 to 2007
$2.6M
NCI NIH HHS R01 CA095153NCI NIH HHS R01 CA122844NCI NIH HHS R01 CA95153
6 · The paper itself

Abstract

purposeAutomated detection of breast boundary is one of the fundamental steps for computer-aided analysis of mammograms. In this study, the authors developed a new dynamic multiple thresholding based breast boundary (MTBB) detection method for digitized mammograms.

methodsA large data set of 716 screen-film mammograms (442 CC view and 274 MLO view) obtained from consecutive cases of an Institutional Review Board approved project were used. An experienced breast radiologist manually traced the breast boundary on each digitized image using a graphical interface to provide a reference standard. The initial breast boundary (MTBB-Initial) was obtained by dynamically adapting the threshold to the gray level range in local regions of the breast periphery. The initial breast boundary was then refined by using gradient information from horizontal and vertical Sobel filtering to obtain the final breast boundary (MTBB-Final). The accuracy of the breast boundary detection algorithm was evaluated by comparison with the reference standard using three performance metrics: The Hausdorff distance (HDist), the average minimum Euclidean distance (AMinDist), and the area overlap measure (AOM).

resultsIn comparison with the authors' previously developed gradient-based breast boundary (GBB) algorithm, it was found that 68%, 85%, and 94% of images had HDist errors less than 6 pixels (4.8 mm) for GBB, MTBB-Initial, and MTBB-Final, respectively. 89%, 90%, and 96% of images had AMinDist errors less than 1.5 pixels (1.2 mm) for GBB, MTBB-Initial, and MTBB-Final, respectively. 96%, 98%, and 99% of images had AOM values larger than 0.9 for GBB, MTBB-Initial, and MTBB-Final, respectively. The improvement by the MTBB-Final method was statistically significant for all the evaluation measures by the Wilcoxon signed rank test (p < 0.0001).

conclusionsThe MTBB approach that combined dynamic multiple thresholding and gradient information provided better performance than the breast boundary detection algorithm that mainly used gradient information.

Indexed as

AlgorithmsArtificial IntelligenceBreast NeoplasmsFemaleHumansMammographyPattern Recognition, AutomatedRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID20175501
PMCPMC2809702

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.