ArticleEuropean journal of nutrition2010
Relationships of dietary patterns with body composition in older adults differ by gender and PPAR-γ Pro12Ala genotype.
Article in European journal of nutrition, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Interaction between Pro12Ala polymorphism of PPARγ2 and diet on adiposity phenotypes.Current atherosclerosis reports · 2014Pooled it
- The Single Nucleotide PolymorphismJournal of obesity · 2018Trial
- Sex Specificities in the Association Between Diet, Physical Activity, and Body Composition Among the Elderly: A Cross-Sectional Study in Florence, Italy.International journal of environmental research and public health · 2025Article
- The Health, Aging, and Body Composition (Health ABC) Study-Ground-Breaking Science for 25 Years and Counting.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Review
- Awareness and use of nutrition information predict measured and self-rated diet quality of older adults in the USA.Public health nutrition · 2021Article
- Failure to vasodilate in response to salt loading blunts renal blood flow and causes salt-sensitive hypertension.Cardiovascular research · 2021Article
- Dietary Patterns and Health Outcomes among African American Maintenance Hemodialysis Patients.Nutrients · 2020Article
- Stability-based validation of dietary patterns obtained by cluster analysis.Nutrition journal · 2017Article
- The importance of gene-environment interactions in human obesity.Clinical science (London, England : 1979) · 2016Review
- Capturing changes in dietary patterns among older adults: a latent class analysis of an ageing Irish cohort.Public health nutrition · 2014Article
- Association of anorexia with sarcopenia in a community-dwelling elderly population: results from the ilSIRENTE study.European journal of nutrition · 2013Article
- Dietary patterns and diet quality among diverse older adults: the University of Alabama at Birmingham Study of Aging.The journal of nutrition, health & aging · 2013Article
- Lifestyle factors modify obesity risk linked to PPARG2 and FTO variants in an elderly population: a cross-sectional analysis in the SUN Project.Genes & nutrition · 2013Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 1 country.
Funding
Abstract
purposeDietary patterns may better capture the multifaceted effects of diet on body composition than individual nutrients or foods. The objective of this study was to investigate the dietary patterns of a cohort of older adults, and examine relationships of dietary patterns with body composition. The influence of a polymorphism in the peroxisome proliferator-activated receptor-γ (PPAR-γ) gene was considered.
methodsThe Health, Aging and Body Composition (Health ABC) Study is a prospective cohort study of 3,075 older adults. Participants' body composition and genetic variation were measured in detail. Food intake was assessed with a semi-quantitative food frequency questionnaire (Block Dietary Data Systems, Berkeley, CA), and dietary patterns of 1,809 participants with complete data were derived by cluster analysis.
resultsSix clusters were identified, including a 'Healthy foods' cluster characterized by higher intake of low-fat dairy products, fruit, whole grains, poultry, fish and vegetables. An interaction was found between dietary patterns and PPAR-γ Pro12Ala genotype in relation to body composition. While Pro/Pro homozygous men and women in the 'Healthy foods' cluster did not differ significantly in body composition from those in other clusters, men with the Ala allele in the 'Healthy foods' cluster had significantly lower levels of adiposity than those in other clusters. Women with the Ala allele in the 'Healthy foods' cluster differed only in right thigh intermuscular fat from those in other clusters.
conclusionsRelationships between diet and body composition in older adults may differ by gender and by genetic factors such as PPAR-γ Pro12Ala genotype.
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Registered trials
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