ArticleClinical lipidology2009
A new model system swims into focus: using the zebrafish to visualize intestinal metabolism in vivo.
Article in Clinical lipidology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 45 citations in OpenAlex.
- Gut distension evokes rapid neural dynamics in vagal and hindbrain populations of larval zebrafish.iScience · 2026Article
- Pancreatic exocrine damage induces beta cell stress in zebrafish larvae.Diabetologia · 2025Article
- Comparison of Different Microalgae Biomass Typologies Used in Rotifers Enrichment for Zebrafish (Aquaculture nutrition · 2025Article
- A high-cholesterol zebrafish diet promotes hypercholesterolemia and fasting-associated liver steatosis.Journal of lipid research · 2024Article
- Fish Playpens: Method for Raising Individual Juvenile Zebrafish on a Recirculating System for Studies Requiring Repeated Measures.Zebrafish · 2024Article
- Zebrafish ApoB-Containing Lipoprotein Metabolism: A Closer Look.Arteriosclerosis, thrombosis, and vascular biology · 2024Review
- Systematic analysis of proximal midgut- and anorectal-originating contractions in larval zebrafish using event feature detection and supervised machine learning algorithms.Neurogastroenterology and motility · 2023Article
- Fish Playpens - Method for raising individual juvenile zebrafish on a recirculating system for studies requiring repeated measures.bioRxiv : the preprint server for biology · 2023Article
- From worms to humans: Understanding intestinal lipid metabolism via model organisms.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2023Review
- Zebrafish: an efficient vertebrate model for understanding role of gut microbiota.Molecular medicine (Cambridge, Mass.) · 2022Review
- Protocol to evaluate hyperlipidemia in zebrafish larvae.STAR protocols · 2022Article
- Model systems for studying the assembly, trafficking, and secretion of apoB lipoproteins using fluorescent fusion proteins.Journal of lipid research · 2020Article
- The zebrafish as a model for gastrointestinal tract-microbe interactions.Cellular microbiology · 2020Review
- Use of Zebrafish in Drug Discovery Toxicology.Chemical research in toxicology · 2020Review
- Polyphenols in the Fermentation Liquid ofFrontiers in immunology · 2020Article
- Dietary cholesterol and apolipoprotein A-I are trafficked in endosomes and lysosomes in the live zebrafish intestine.American journal of physiology. Gastrointestinal and liver physiology · 2019Article
- A novel system to quantify intestinal lipid digestion and transport.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2018Article
- Intestinal epithelial cell caveolin 1 regulates fatty acid and lipoprotein cholesterol plasma levels.Disease models & mechanisms · 2017Article
- High-fat Feeding Paradigm for Larval Zebrafish: Feeding, Live Imaging, and Quantification of Food Intake.Journal of visualized experiments : JoVE · 2016Article
- Zebrafish as a model for apolipoprotein biology: comprehensive expression analysis and a role for ApoA-IV in regulating food intake.Disease models & mechanisms · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Many fundamental questions remain regarding the cellular and molecular mechanisms of digestive lipid metabolism. One major impediment to answering important questions in the field has been the lack of a tractable and sufficiently complex model system. Until recently, most studies of lipid metabolism have been performed in vitro or in mice, yet each approach possesses certain limitations. The zebrafish (Danio rerio) offers an excellent model system in which to study lipid metabolism in vivo, owing to its small size, genetic tractability and optical clarity. Fluorescent lipid dyes and optical reporters of lipid-modifying enzymes are now being used in live zebrafish to generate visible readouts of digestive physiology. Here we review recent advances in visualizing intestinal lipid metabolism in live larval zebrafish.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.