Inflammatory cytokines in heart failure: roles in aetiology and utility as biomarkers.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

21 citing papers in PubMed.

1. SERCA2a dysfunction in the pathophysiology of heart failure with preserved ejection fraction: a direct role is yet to be established.Heart failure reviews · 2025
   Review
2. Interplay between Pro-inflammatory Mediators and Oxidative Stressinvolved Recurrent Chronic Heart Failure in Elderly Patients with Coronary Stents.Current medicinal chemistry · 2025
   Article
3. The favourable alliance between CardioMEMS and levosimendan in patients with advanced heart failure.ESC heart failure · 2024
   Article
4. An Evaluation of Plasma TNF, VEGF-A, and IL-6 Determination as a Risk Marker of Atherosclerotic Vascular Damage in Early-Onset CAD Patients.Journal of clinical medicine · 2024
   Article
5. The association between lymphocyte-to-monocyte ratio and all-cause mortality in obese hypertensive patients with diabetes and without diabetes: results from the cohort study of NHANES 2001-2018.Frontiers in endocrinology · 2024
   Article
6. The role of inflammation and antioxidant defenses in the cardiotoxicity of doxorubicin in elderly CD-1 male mice.Archives of toxicology · 2023
   Article
7. Application Value of Systemic Inflammatory Indexes in the Clinical Evaluation of Patients with Heart Failure with Preserved Ejection Fraction (HFpEF).Medicina (Kaunas, Lithuania) · 2022
   Article
8. Electrocardiographic abnormalities in patients with COVID-19 pneumonia and raised interleukin-6.Journal of family medicine and primary care · 2022
   Article
9. Cariporide Attenuates Doxorubicin-Induced Cardiotoxicity in Rats by Inhibiting Oxidative Stress, Inflammation and Apoptosis Partly Through Regulation of Akt/GSK-3β and Sirt1 Signaling Pathway.Frontiers in pharmacology · 2022
   Article
10. Could inflammation contribute to salivary gland dysfunction in patients with chronic heart failure?Frontiers in immunology · 2022
    Observational
11. Should metformin remain the first-line therapy for treatment of type 2 diabetes?Therapeutic advances in endocrinology and metabolism · 2021
    Review
12. Successful treatment of acute heart failure in COVID-19-induced cytokine storm with tocilizumab: a case report.European heart journal. Case reports · 2020
    Article
13. Thyroid storm: a case of haemodynamic failure promptly reversed by aggressive medical therapy with antithyroid agents and steroid pulse.BMJ case reports · 2018
    Review
14. Gene expression and levels of IL-6 and TNFα in PBMCs correlate with severity and functional class in patients with chronic heart failure.Irish journal of medical science · 2018
    Article
15. Mesenchymal Stromal Cells Cultured in Serum from Heart Failure Patients Are More Resistant to Simulated Chronic and Acute Stress.Stem cells international · 2018
    Article
16. Metformin and ageing: improving ageing outcomes beyond glycaemic control.Diabetologia · 2017
    Review
17. Evaluation of Innate Immunity Biomarkers on Admission and at Discharge From an Acute Heart Failure Episode.Journal of clinical laboratory analysis · 2016
    Observational
18. Pressure overload-induced cardiac remodeling and dysfunction in the absence of interleukin 6 in mice.Laboratory investigation; a journal of technical methods and pathology · 2012
    Article
19. Ameliorated stress related proteins are associated with improved cardiac function by sarcoplasmic reticulum calcium ATPase gene transfer in heart failure.Journal of geriatric cardiology : JGC · 2012
    Article
20. Bench-to-bedside review: Neonatal sepsis-redox processes in pathogenesis.Critical care (London, England) · 2012
    Review

Corrections and comments

• Comment on
  Relationship of interleukin-6 with regional and global left-ventricular function in asymptomatic individuals without clinical cardiovascular disease: insights from the Multi-Ethnic Study of Atherosclerosis.2010

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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