Evidence map›Paper›PMID 20172550›Full record

ArticleThe Journal of urology2010

Variation among internet based calculators in predicting spontaneous resolution of vesicoureteral reflux.

Jonathan C Routh, Edward M Gong, Glenn M Cannon, Richard N Yu, Patricio C Gargollo, Caleb P Nelson

Open access · greenAbstract read
In one paragraph

Article in The Journal of urology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Relevance of current guidelines in the management of VUR.European journal of pediatrics · 2014
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jonathan C RouthDepartment of Urology, Children's Hospital Boston, Boston, Massachusetts 02115, USA.
Edward M Gong
Glenn M Cannon
Richard N Yu
Patricio C Gargollo
Caleb P Nelson
Boston Children's Hospital · USThe University of Texas Southwestern Medical Center · US

Funding

Training in Child Health Services Research and Implementation ScienceT32HS000063 · AHRQ · CHILDREN'S HOSPITAL BOSTON · PI GARABEDIAN, LAURA FADEN, WALSH, KATHLEEN ELIZABETH · 1994 to 2024
$7.6M
Research Training in Pediatric Urology/CHB T32T32DK060442 · NIDDK · CHILDREN'S HOSPITAL BOSTON · PI ADAM, ROSALYN M · 2002 to 2023
$2.5M
Comparative Effectiveness of Vesicoureteral Reflux Treatments in ChildrenK08DK100534 · NIDDK · DUKE UNIVERSITY · PI ROUTH, JONATHAN C · 2014 to 2018
$671k
AHRQ HHS T32-HS000063NIDDK NIH HHS K08 DK100534NIDDK NIH HHS T32 DK060442
6 · The paper itself

Abstract

purposeAn increasing number of parents and practitioners use the Internet for health related purposes, and an increasing number of models are available on the Internet for predicting spontaneous resolution rates for children with vesicoureteral reflux. We sought to determine whether currently available Internet based calculators for vesicoureteral reflux resolution produce systematically different results. MATERIALS AND

methodsFollowing a systematic Internet search we identified 3 Internet based calculators of spontaneous resolution rates for children with vesicoureteral reflux, of which 2 were academic affiliated and 1 was industry affiliated. We generated a random cohort of 100 hypothetical patients with a wide range of clinical characteristics and entered the data on each patient into each calculator. We then compared the results from the calculators in terms of mean predicted resolution probability and number of cases deemed likely to resolve at various cutoff probabilities.

resultsMean predicted resolution probabilities were 41% and 36% (range 31% to 41%) for the 2 academic affiliated calculators and 33% for the industry affiliated calculator (p = 0.02). For some patients the calculators produced markedly different probabilities of spontaneous resolution, in some instances ranging from 24% to 89% for the same patient. At thresholds greater than 5%, 10% and 25% probability of spontaneous resolution the calculators differed significantly regarding whether cases would resolve (all p <0.0001).

conclusionsPredicted probabilities of spontaneous resolution of vesicoureteral reflux differ significantly among Internet based calculators. For certain patients, particularly those with a lower probability of spontaneous resolution, these differences can significantly influence clinical decision making.

Indexed as

InternetVesico-Ureteral RefluxChildChild, PreschoolFemaleForecastingHumansInfantMaleModels, StatisticalPrognosisRemission, Spontaneous

Identifiers

PMID20172550
PMCPMC2874745
OpenAlexW2085758202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.