Evidence map›Paper›PMID 20172487›Full record

ReviewGenomics, proteomics & bioinformatics2009

A brief review on the mechanisms of miRNA regulation.

Yimei Cai, Xiaomin Yu, Songnian Hu, Jun Yu

Open access · goldAbstract readReview
In one paragraph

Review in Genomics, proteomics & bioinformatics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 514 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
514citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

514 citing papers in PubMed, 2 syntheses or guidelines pooled it, 1,007 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  11. Study on Regulatory Mechanism ofMolecules (Basel, Switzerland) · 2026
    Article
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  13. Plasma Expression andBiomolecules · 2026
    Article
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  16. Review
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454 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yimei CaiKey Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, China.
Xiaomin Yu
Songnian Hu
Jun Yu
Beijing Institute of Genomics · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are a class of short, endogenously-initiated non-coding RNAs that post-transcriptionally control gene expression via either translational repression or mRNA degradation. It is becoming evident that miRNAs are playing significant roles in regulatory mechanisms operating in various organisms, including developmental timing and host-pathogen interactions as well as cell differentiation, proliferation, apoptosis and tumorigenesis. Likewise, as a regulatory element, miRNA itself is coordinatively modulated by multifarious effectors when carrying out basic functions, such as SNP, miRNA editing, methylation and circadian clock. This mini-review summarized the current understanding of interactions between miRNAs and their targets, including recent advancements in deciphering the regulatory mechanisms that control the biogenesis and functionality of miRNAs in various cellular processes.

Indexed as

Gene Expression RegulationGene Regulatory NetworksAnimalsHumansMicroRNAsMicroRNAs

Identifiers

PMID20172487
PMCPMC5054406
OpenAlexW1990061381

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.