ArticleJournal of the Chinese Medical Association : JCMA2010
Seroprevalence of antibodies to pandemic (H1N1) 2009 influenza virus among hospital staff in a medical center in Taiwan.
Article in Journal of the Chinese Medical Association : JCMA, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Immunogenicity and safety levels of inactivated quadrivalent influenza vaccine in healthy adults via meta-analysis.Human vaccines & immunotherapeutics · 2021Pooled it
- Pooled it
- The Use of Residual Blood Specimens in Seroprevalence Studies for Vaccine-Preventable Diseases: A Scoping Review.Vaccines · 2025Review
- Infection in Health Personnel with High and Low Levels of Exposure in a Hospital Setting during the H1N1 2009 Influenza A Pandemic.PloS one · 2016Article
- Pandemic influenza A(H1N1)pdm09: risk of infection in primary healthcare workers.The British journal of general practice : the journal of the Royal College of General Practitioners · 2013Article
- Influenza serological studies to inform public health action: best practices to optimise timing, quality and reporting.Influenza and other respiratory viruses · 2013Article
- Seropositivity for influenza A(H1N1)pdm09 virus among frontline health care personnel.Emerging infectious diseases · 2013Article
- Seroprevalence of antibodies to the influenza A (H1N1) virus among healthcare workers prior to the 2009 pandemic peak.Enfermedades infecciosas y microbiologia clinica · 2012Article
- H1N1v at a seroepidemiological glance: is the nightmare over?European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012Article
- Exhaled air dispersion during coughing with and without wearing a surgical or N95 mask.PloS one · 2012Article
- Incidence of H1N1 2009 virus infection through the analysis of paired plasma specimens among blood donors, France.PloS one · 2012Article
- High incidence of severe influenza among individuals over 50 years of age.Clinical and vaccine immunology : CVI · 2011Article
- Seroprevalence of antibodies to influenza A/H1N1/2009 among transmission risk groups after the second wave in Mexico, by a virus-free ELISA method.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2011Article
- Risk factors for pandemic H1N1 2009 infection in healthcare personnel of four general hospitals.The Journal of infection · 2011Article
- Comparability of different methods for estimating influenza infection rates over a single epidemic wave.American journal of epidemiology · 2011Article
- Seroprevalence of antibody to pandemic influenza A (H1N1) 2009 among healthcare workers after the first wave in Hong Kong.The Journal of hospital infection · 2011Article
- Seroprevalence to influenza A(H1N1) 2009 virus--where are we?Clinical and vaccine immunology : CVI · 2011Review
- Pandemic response lessons from influenza H1N1 2009 in Asia.Respirology (Carlton, Vic.) · 2011Review
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Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe pandemic (H1N1) 2009 influenza emerged in April 2009 and spread rapidly and broadly all over the world. In addition to specific antiviral agents, massive vaccination is thought to be the most effective way of controlling the transmission. To understand the prevaccination status of certain risk groups, this study compared the baseline sero-prevalence of antibodies to the pandemic (H1N1) 2009 influenza virus among hospital staff with different contact risks and that of the general population.
methodsA total of 295 serum samples from hospital staff and 244 control serum samples from people who came for physical check-up (control group) were collected between October 2009 and November 2009 before the massive vaccination campaign. The hospital staff was divided into first-line risk personnel (group 1) and second-line risk personnel (group 2) according to their potential contact risks. Hemagglutination-inhibition (HI) tests were conducted to determine the individual serological status. The seropositive rate (SPR, defined as the proportion with HI titer >/= 1:40) of antibodies to H1N1 influenza virus and its geometric mean titer (GMT) were calculated and compared among the different groups.
resultsThe mean ages and sex ratio (% male) of the hospital staff and control groups were 36.9 +/- 10.6 years and 52.0 +/- 12.6 years, and 24.4% and 57.6%, respectively. The SPR of the antibodies to H1N1 influenza virus of the hospital staff was significantly higher than that of the control group (20.0%vs. 2.9%, p < 0.001). Furthermore, the SPR antibodies to H1N1 influenza virus of group 1 were significantly higher than that of group 2 (30.8%vs. 12.6%, p < 0.001). However, the GMT of antibodies to H1N1 influenza virus of the hospital staff was not significantly different from that of the control group (p = 0.925).
conclusionThe SPR of antibodies against the pandemic (H1N1) 2009 virus in the hospital staff was higher than that in the general population, reflecting a higher contact risk. Prevaccination surveillance of the immune status of different risk groups may help to prioritize which groups should be vaccinated first.
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